PXD037048

PXD037048 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Profiling Sulfur(VI) Fluorides as Reactive Functionalities for Chemical Biology Tools and Expansion of the Ligandable Proteome
Description	Here, we profiled sulfur(VI) fluorides (SVI-F) as reactive functionalities that can modify multiple residues including Lys, Tyr, His and Ser, thus offering utility for targeting almost any protein. These studies provided an in-depth understanding of SVI-F functionalities, including hydrolytic stability, protein reactivity and utility in chemoproteomics
HostingRepository	PRIDE
AnnounceDate	2024-03-18
AnnouncementXML	Submission_2024-03-18_03:00:19.784.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Aini Vuorinen
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	acetylated residue
Instrument	Orbitrap Fusion Lumos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2022-09-27 11:40:27	ID requested
⏵ 1	2024-03-18 03:00:20	announced

Publication List

Gilbert KE, Vuorinen A, Aatkar A, Pog, á, ny P, Pettinger J, Grant EK, Kirkpatrick JM, Rittinger K, House D, Burley GA, Bush JT, Profiling Sulfur(VI) Fluorides as Reactive Functionalities for Chemical Biology Tools and Expansion of the Ligandable Proteome. ACS Chem Biol, 18(2):285-295(2023) [pubmed]
10.1021/acschembio.2c00633;

Gilbert KE, Vuorinen A, Aatkar A, Pog, á, ny P, Pettinger J, Grant EK, Kirkpatrick JM, Rittinger K, House D, Burley GA, Bush JT, Profiling Sulfur(VI) Fluorides as Reactive Functionalities for Chemical Biology Tools and Expansion of the Ligandable Proteome. ACS Chem Biol, 18(2):285-295(2023) [pubmed]

10.1021/acschembio.2c00633;

Keyword List

submitter keyword: covalent probes, covalent fragment screening, sulfonyl fluoride, chemical biology

submitter keyword: covalent probes, covalent fragment screening, sulfonyl fluoride, chemical biology

Contact List

Jacob Bush
contact affiliation	GSK
contact email	jacob.x.bush@gsk.com
lab head
Aini Vuorinen
contact affiliation	GSK
contact email	aini.e.vuorinen@gsk.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/03/PXD037048
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/03/PXD037048

PRIDE project URI

Repository Record List

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