PXD036916 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | LC-MSMS analysis of bear muscle mitochondria during hibernation |
| Description | During hibernation, the physiology of bears is characterized by strong metabolic depression. In skeletal muscles, lipids are used as the main energy fuels although their oxidation rate is reduced, and glycolysis appears maintained likely feeding the Cori cycle. Mitochondria no doubt play an essential role in such an adaptation. However, neither their activity nor their protein content had been analysed earlier. To fill this gap, this study analysed the bear (Ursus arctos) skeletal muscle mitochondrial fraction using shotgun proteomics to compare hibernation to the summer-active period. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-03-02 |
| AnnouncementXML | Submission_2026-03-01_17:10:46.716.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Fabrice BERTILE |
| SpeciesList | scientific name: Ursus arctos arctos (European brown bear); NCBI TaxID: NEWT:563924; |
| ModificationList | acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | Q Exactive Plus |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
| 0 | 2022-09-21 15:17:46 | ID requested | |
| ⏵ 1 | 2026-03-01 17:10:47 | announced | |
Publication List
| 10.1111/apha.70177; |
| Bergouignan A, Noone J, Brun C, Cussonneau L, Geffroy A, Coudy-Gandilhon C, Chery I, Evans AL, Arnemo JM, Kindberg J, Gauquelin-Koch G, O'Gorman D, Lefai E, Bertile F, The Preservation of Muscle Mitochondrial Machinery During Hypometabolic Hibernation in Scandinavian Brown Bears (Ursus arctos). Acta Physiol (Oxf), 242(4):e70177(2026) [pubmed] |
Keyword List
| submitter keyword: LC-MSMS, metabolic depression, temperature,Bear, hibernation |
Contact List
| Sarah Cianférani |
| contact affiliation | Laboratoire de Spectrométrie de Masse BioOrganique, Analytical Science department, IPHC, CNRS, Strasbourg University, UMR7178, Strasbourg, France |
| contact email | sarah.cianferani@unistra.fr |
| lab head | |
| Fabrice BERTILE |
| contact affiliation | CNRS |
| contact email | fbertile@unistra.fr |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
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| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD036916
- Label: PRIDE project
- Name: LC-MSMS analysis of bear muscle mitochondria during hibernation