PXD036852
PXD036852 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Systematic analysis of cardiac transcriptome and proteome in Tmem43 knockout mice reveals the defect of heart muscle contraction |
| Description | Here, we profiled the transcriptome and proteome of the hearts of the Tmem43 null mouse via RNA-Seq and mass spectral. Functional enrichments of the differentially expressed genes and differentially expressed proteins both revealed that the muscle contraction was the major pathway influenced by TMEM43 deficiency. Further study indicated that BMP2 signaling pathway and mitochondria may mediate TMEM43’s role in hearts. These results expand our knowledge of the roles of TMEM43 in hearts. |
| HostingRepository | iProX |
| AnnounceDate | 2022-09-20 |
| AnnouncementXML | Submission_2022-09-19_20:12:13.653.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Guoxing Zheng |
| SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2022-09-19 20:09:39 | ID requested | |
| ⏵ 1 | 2022-09-19 20:12:14 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Tmem43 knockout mice, cardiac muscle contraction, transcriptome, proteome |
Contact List
| Chengming Zhu | |
|---|---|
| contact affiliation | Sun Yat-sen University |
| contact email | zhuchm3@mail.sysu.edu.cn |
| lab head | |
| Guoxing Zheng | |
| contact affiliation | Sun Yat-sen University |
| contact email | opqsky@126.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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