PXD036821
PXD036821 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | The accessory protein ORF6 contributes to SARS-CoV-2 pathogenesis by regulating host and viral gene expression |
Description | We generated a SARS-CoV-2 virus in the Wuhan background with a deletion of the Orf6 gene. We then performed mass spectrometry abundance proteomics and phosphoproteomics analysis of infected cells. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_06:30:47.838.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Mehdi Bouhaddou |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; scientific name: Severe acute respiratory syndrome coronavirus 2; NCBI TaxID: 2697049; |
ModificationList | phosphorylated residue; acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Orbitrap Fusion Lumos; Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2022-09-17 15:10:34 | ID requested | |
1 | 2024-02-15 17:50:26 | announced | |
⏵ 2 | 2024-10-22 06:30:48 | announced | 2024-10-22: Updated project metadata. |
Publication List
Kehrer T, Cupic A, Ye C, Yildiz S, Bouhaddou M, Crossland NA, Barrall EA, Cohen P, Tseng A, Ç, a, ğ, atay T, Rathnasinghe R, Flores D, Jangra S, Alam F, Mena I, Aslam S, Saqi A, Rutkowska M, Ummadi MR, Pisanelli G, Richardson RB, Veit EC, Fabius JM, Soucheray M, Polacco BJ, Ak B, Marin A, Evans MJ, Swaney DL, Gonzalez-Reiche AS, Sordillo EM, van Bakel H, Simon V, Zuliani-Alvarez L, Fontoura BMA, Rosenberg BR, Krogan NJ, Martinez-Sobrido L, Garc, í, a-Sastre A, Miorin L, Impact of SARS-CoV-2 ORF6 and its variant polymorphisms on host responses and viral pathogenesis. Cell Host Microbe, 31(10):1668-1684.e12(2023) [pubmed] |
10.1016/j.chom.2023.08.003; |
Keyword List
ProteomeXchange project tag: Sars-cov-2, Covid-19 |
submitter keyword: SARS-CoV-2, orf6, COVID, coronavirus, phosphoproteomics, infection, COVID-19 |
Contact List
Nevan J. Krogan | |
---|---|
contact affiliation | Professor, Department of Cellular and Molecular Pharmacology |
contact email | nevan.krogan@ucsf.edu |
lab head | |
Mehdi Bouhaddou | |
contact affiliation | UCSF |
contact email | mehdibouhaddou@gmail.com |
dataset submitter |
Full Dataset Link List
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/02/PXD036821 |
PRIDE project URI |
Repository Record List
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