PXD036800 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Urinary proteome related to coronary artery disease and aortic stenosis |
Description | Coronary artery disease (CAD) and the frequently coexisting aortic valve stenosis (AS) are the heart diseases accounting for the highest proportion of cardiac surgeries. Routine biomarkers for an earl detection of either of these atherosclerotic-rooted conditions would be important to anticipate the diagnosis and to evaluate their severity with imaging techniques before they become advanced to the point where intervention or surgery have limited therapeutic benefit. Urine is an attractive biofluid for biomarker assessment, provided the noninvasive nature of its collection. Therefore, we conducted a shotgun proteomics analysis of urine collected from 12 CAD and/or AS patients and 11 cardiovascular disease-free controls, aiming at identification of putative molecular candidates that could differentiate these diseases from healthy subjects |
HostingRepository | PRIDE |
AnnounceDate | 2023-11-14 |
AnnouncementXML | Submission_2023-11-14_08:25:50.579.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Antje Dittmann |
SpeciesList | scientific name: Acyrthosiphon pisum (Pea aphid); NCBI TaxID: 7029; scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Orbitrap Exploris 480 |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-09-17 04:02:08 | ID requested | |
1 | 2022-12-18 15:11:55 | announced | |
⏵ 2 | 2023-11-14 08:25:51 | announced | 2023-11-14: Updated project metadata. |
Publication List
Perp, é, tuo L, Barros AS, Dalsuco J, Nogueira-Ferreira R, Resende-Gon, ç, alves P, Falc, ã, o-Pires I, Ferreira R, Leite-Moreira A, Trindade F, Vitorino R, Coronary Artery Disease and Aortic Valve Stenosis: A Urine Proteomics Study. Int J Mol Sci, 23(21):(2022) [pubmed] |
Keyword List
ProteomeXchange project tag: EPIC-XS |
submitter keyword: Human, aortic valve stenosis, urine, molecular marker, coronary artery disease |
Contact List
Rui Vitorino |
contact affiliation | iBiMED, Department of Medical Sciences, University of Aveiro, Aveiro Cardiovascular R&D Centre – UnIC@RISE, Department of Surgery and Physiology, Faculty of Medicine of the University of Porto, Porto, Portugal |
contact email | rvitorino@ua.pt |
lab head | |
Antje Dittmann |
contact affiliation | ETH |
contact email | antje.dittmann@gmail.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD036800
- Label: PRIDE project
- Name: Urinary proteome related to coronary artery disease and aortic stenosis