PXD036800

PXD036800 is an original dataset announced via ProteomeXchange.

Title	Urinary proteome related to coronary artery disease and aortic stenosis
Description	Coronary artery disease (CAD) and the frequently coexisting aortic valve stenosis (AS) are the heart diseases accounting for the highest proportion of cardiac surgeries. Routine biomarkers for an earl detection of either of these atherosclerotic-rooted conditions would be important to anticipate the diagnosis and to evaluate their severity with imaging techniques before they become advanced to the point where intervention or surgery have limited therapeutic benefit. Urine is an attractive biofluid for biomarker assessment, provided the noninvasive nature of its collection. Therefore, we conducted a shotgun proteomics analysis of urine collected from 12 CAD and/or AS patients and 11 cardiovascular disease-free controls, aiming at identification of putative molecular candidates that could differentiate these diseases from healthy subjects
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_08:25:50.579.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Antje Dittmann
SpeciesList	scientific name: Acyrthosiphon pisum (Pea aphid); NCBI TaxID: 7029; scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Exploris 480

Revision	Datetime	Status	ChangeLog Entry
0	2022-09-17 04:02:08	ID requested
1	2022-12-18 15:11:55	announced
⏵ 2	2023-11-14 08:25:51	announced	2023-11-14: Updated project metadata.

Perp, é, tuo L, Barros AS, Dalsuco J, Nogueira-Ferreira R, Resende-Gon, ç, alves P, Falc, ã, o-Pires I, Ferreira R, Leite-Moreira A, Trindade F, Vitorino R, Coronary Artery Disease and Aortic Valve Stenosis: A Urine Proteomics Study. Int J Mol Sci, 23(21):(2022) [pubmed]

ProteomeXchange project tag: EPIC-XS

submitter keyword: Human, aortic valve stenosis, urine, molecular marker, coronary artery disease

Rui Vitorino
contact affiliation	iBiMED, Department of Medical Sciences, University of Aveiro, Aveiro Cardiovascular R&D Centre – UnIC@RISE, Department of Surgery and Physiology, Faculty of Medicine of the University of Porto, Porto, Portugal
contact email	rvitorino@ua.pt
lab head
Antje Dittmann
contact affiliation	ETH
contact email	antje.dittmann@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/12/PXD036800

PRIDE project URI

• PRIDE
  1. PXD036800
     1. Label: PRIDE project
     2. Name: Urinary proteome related to coronary artery disease and aortic stenosis