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PXD036800

PXD036800 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleUrinary proteome related to coronary artery disease and aortic stenosis
DescriptionCoronary artery disease (CAD) and the frequently coexisting aortic valve stenosis (AS) are the heart diseases accounting for the highest proportion of cardiac surgeries. Routine biomarkers for an earl detection of either of these atherosclerotic-rooted conditions would be important to anticipate the diagnosis and to evaluate their severity with imaging techniques before they become advanced to the point where intervention or surgery have limited therapeutic benefit. Urine is an attractive biofluid for biomarker assessment, provided the noninvasive nature of its collection. Therefore, we conducted a shotgun proteomics analysis of urine collected from 12 CAD and/or AS patients and 11 cardiovascular disease-free controls, aiming at identification of putative molecular candidates that could differentiate these diseases from healthy subjects
HostingRepositoryPRIDE
AnnounceDate2023-11-14
AnnouncementXMLSubmission_2023-11-14_08:25:50.579.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterAntje Dittmann
SpeciesList scientific name: Acyrthosiphon pisum (Pea aphid); NCBI TaxID: 7029; scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListacetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentOrbitrap Exploris 480
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-09-17 04:02:08ID requested
12022-12-18 15:11:55announced
22023-11-14 08:25:51announced2023-11-14: Updated project metadata.
Publication List
Perp, é, tuo L, Barros AS, Dalsuco J, Nogueira-Ferreira R, Resende-Gon, ç, alves P, Falc, ã, o-Pires I, Ferreira R, Leite-Moreira A, Trindade F, Vitorino R, Coronary Artery Disease and Aortic Valve Stenosis: A Urine Proteomics Study. Int J Mol Sci, 23(21):(2022) [pubmed]
Keyword List
ProteomeXchange project tag: EPIC-XS
submitter keyword: Human, aortic valve stenosis, urine, molecular marker, coronary artery disease
Contact List
Rui Vitorino
contact affiliationiBiMED, Department of Medical Sciences, University of Aveiro, Aveiro Cardiovascular R&D Centre – UnIC@RISE, Department of Surgery and Physiology, Faculty of Medicine of the University of Porto, Porto, Portugal
contact emailrvitorino@ua.pt
lab head
Antje Dittmann
contact affiliationETH
contact emailantje.dittmann@gmail.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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