PXD036638

PXD036638 is an original dataset announced via ProteomeXchange.

Title	A role for complement in idiopathic pulmonary fibrosis
Description	The pathogenesis of idiopathic pulmonary fibrosis is multifactorial and characterized by progressive fibrosis and excessive accumulation of extracellular matrix in the interstitium of the lung, and driven by an imbalance between anti-fibrotic and pro-fibrotic factors leading to collagen deposition. In the present study we wanted to identify proteins involved in these processes, and performed high-resolution proteomic profiling of bronchoalveolar lavage (BAL) from IPF patients and controls. The proteomic analysis of BAL demonstrated that the complement system was highly differentially regulated in IPF patients as compared with controls.
HostingRepository	PRIDE
AnnounceDate	2023-07-31
AnnouncementXML	Submission_2023-07-31_00:15:11.789.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	TuulaNyman
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2022-09-12 05:24:20	ID requested
⏵ 1	2023-07-31 00:15:12	announced

Dataset with its publication pending

submitter keyword: proteomics, bronchoalveolar lavage, idiopathic pulmonary fibrosis,interstitial lung disease, terminal complement complex

TuulaNyman
contact affiliation	Head of Proteomics
contact email	tuula.nyman@medisin.uio.no
lab head
TuulaNyman
contact affiliation	University of Oslo
contact email	tuula.nyman@medisin.uio.no
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/07/PXD036638

PRIDE project URI

• PRIDE
  1. PXD036638
     1. Label: PRIDE project
     2. Name: A role for complement in idiopathic pulmonary fibrosis