PXD036507 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Glycosylation Patterns on Collagen α1(I) and Collagen α2(I) resemble a lock and key arrangement |
Description | Col1 from the skins of 4 animals (cow, deer, goat and sheep) were purified, then used mass spectrometry and proteomic techniques to identify lysines that were oxidised, galactosylated, glucosylgalactosylated, or glycated in its ma-ture sequence. We found 18 out of the 38 lysines in collagen type 1α1, (Col1A1) and 7 of the 30 lysines in collagen type 1α2 (Col1A2) were glycosylated. Six of these modifications had not been reported before, and included a lysine involved in cross linking collagen molecules. Mapping the positions of these modifications on the ColA1 and Col1A2 sequences showed they were complimentary and resembled a lock and key arrangement. |
HostingRepository | PRIDE |
AnnounceDate | 2023-11-14 |
AnnouncementXML | Submission_2023-11-14_08:57:37.461.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Trevor Loo |
SpeciesList | scientific name: Capra hircus x Ovis aries; NCBI TaxID: 2666255; scientific name: Bos taurus (Bovine); NCBI TaxID: 9913; |
ModificationList | carbamoylated residue; hexose glycated L-lysine; monohydroxylated residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-09-05 08:55:13 | ID requested | |
1 | 2023-05-23 17:12:31 | announced | |
⏵ 2 | 2023-11-14 08:57:37 | announced | 2023-11-14: Updated project metadata. |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: hydroxylation, in-gel digestion,glycosylation, lysine, collagen, type 1 |
Contact List
Gill Norris |
contact affiliation | Massey University |
contact email | G.Norris@massey.ac.nz |
lab head | |
Trevor Loo |
contact affiliation | Massey University |
contact email | t.s.loo@massey.ac.nz |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD036507
- Label: PRIDE project
- Name: Glycosylation Patterns on Collagen α1(I) and Collagen α2(I) resemble a lock and key arrangement