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PXD036364

PXD036364 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomics analyses reveal the novel targets of spermine alleviating diabetic cardiomyopathy
DescriptionDiabetic cardiomyopathy (DCM) is one of the most serious complications of diabetes. Recent cardiology studies suggest that spermine has cardioprotective effect. Here, we used proteomics analyses to reveal the underlying research target in type 2 diabetic mouse model treated with spermine. Left ventricular tissue was excised from 9 mice (Control group, 3; T2D group(db/db mouse), 3; T2D+SP group, 3) and analyzed. Quantitative analysis of the global proteome were detected using 4D label-free technique,and differentially expressed proteins (DEPs) were used to perform bioinformatic analyses.
HostingRepositoryPRIDE
AnnounceDate2022-10-13
AnnouncementXMLSubmission_2022-10-13_03:24:21.301.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterHuiYuan
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Exploris 480
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-08-28 03:24:36ID requested
12022-10-13 03:24:21announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Diabetic cardiomyopathy
Spermine
Proteomic analysis
Bioinformatic;db/db mouse
Contact List
HuiYuan
contact affiliationDepartment of Pathophysiology, Mudanjiang Medical University
contact emailhuiyuan1982@126.com
lab head
HuiYuan
contact affiliationMudanjiang Medical University
contact emailhuiyuan1982@126.com
dataset submitter
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Dataset FTP location
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