PXD036336

PXD036336 is an original dataset announced via ProteomeXchange.

Title	Proteins of the translation initiation complex in Arabidopsis thaliana infected or not with potyvirus
Description	Successful subversion of translation initiation factors 4E and 4G determines the infection success of potyviruses, the largest group of viruses affecting plants. Functional redundancy among these factors allows to engineer resistances through their genetic inactivation, however recent findings indicate that this strategy may be deleterious for the plant health and virus susceptibility. Here, we explored the cause of these adverse effects by studying the role of the Arabidopsis eIF4E1, which inactivation was previously reported not only to confer plant virus resistance, but also to induce increased susceptibility to the potyvirus turnip mosaic virus (TuMV). We report that eIF4E1 is required to maintain the global plant translational activity and to restrict TuMV accumulation during infection, as its absence is associated with a favoured virus multiplication over host translation.
HostingRepository	PRIDE
AnnounceDate	2023-10-26
AnnouncementXML	Submission_2023-10-25_23:31:51.063.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD036336
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	YohannCouté
SpeciesList	scientific name: Arabidopsis thaliana (Mouse-ear cress); NCBI TaxID: 3702;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2022-08-26 07:55:35	ID requested
⏵ 1	2023-10-25 23:31:51	announced

10.6019/PXD036336;

submitter keyword: potyvirus turnip mosaic virus, pull-down assay,Arabidopsis, translation initiation complex, nanoLC-MS/MS

YohannCouté
contact affiliation	EDyP
contact email	yohann.coute@cea.fr
lab head
YohannCouté
contact affiliation	EDyP
contact email	yohann.coute@cea.fr
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD036336
     1. Label: PRIDE project
     2. Name: Proteins of the translation initiation complex in Arabidopsis thaliana infected or not with potyvirus