PXD036324 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | One-pot comparative analysis and characterization of young and old mice brain lysates |
Description | A comparison of different energetics based techniques for the characterization of young and old mice brain cell lysates. The techniques of stability of proteins from rates of oxidation (SPROX), thermal proteome profiling (TPP), Limited Proteolysis (LiP) and conventional expression level analyses were compared and the relative advantages and disadvantages are discussed. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_06:42:02.668.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Morgan Bailey |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | TMT6plex-126 reporter+balance reagent acylated residue; methylthiolated residue; monohydroxylated residue |
Instrument | Orbitrap Exploris 480 |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-08-26 07:18:33 | ID requested | |
1 | 2024-05-23 01:05:34 | announced | |
⏵ 2 | 2024-10-22 06:42:07 | announced | 2024-10-22: Updated project metadata. |
Publication List
10.1021/jasms.2c00248; |
Bailey MA, Tang Y, Park HJ, Fitzgerald MC, Comparative Analysis of Protein Folding Stability-Based Profiling Methods for Characterization of Biological Phenotypes. J Am Soc Mass Spectrom, 34(3):383-393(2023) [pubmed] |
Keyword List
submitter keyword: Thermodynamics, thermal denaturation, chemical denaturation, protein folding |
Contact List
Michael C. Fitzgerald |
contact affiliation | Professor of Chemistry Department of Chemistry Duke University |
contact email | michael.c.fitzgerald@duke.edu |
lab head | |
Morgan Bailey |
contact affiliation | Duke University Department of Chemistry |
contact email | morgan.a.bailey@duke.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/05/PXD036324 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD036324
- Label: PRIDE project
- Name: One-pot comparative analysis and characterization of young and old mice brain lysates