PXD036324

PXD036324 is an original dataset announced via ProteomeXchange.

Title	One-pot comparative analysis and characterization of young and old mice brain lysates
Description	A comparison of different energetics based techniques for the characterization of young and old mice brain cell lysates. The techniques of stability of proteins from rates of oxidation (SPROX), thermal proteome profiling (TPP), Limited Proteolysis (LiP) and conventional expression level analyses were compared and the relative advantages and disadvantages are discussed.
HostingRepository	PRIDE
AnnounceDate	2024-05-23
AnnouncementXML	Submission_2024-05-23_01:05:33.399.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Morgan Bailey
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue; methylthiolated residue; monohydroxylated residue
Instrument	Orbitrap Exploris 480

Revision	Datetime	Status	ChangeLog Entry
0	2022-08-26 07:18:33	ID requested
⏵ 1	2024-05-23 01:05:34	announced

10.1021/jasms.2c00248;

Bailey MA, Tang Y, Park HJ, Fitzgerald MC, Comparative Analysis of Protein Folding Stability-Based Profiling Methods for Characterization of Biological Phenotypes. J Am Soc Mass Spectrom, 34(3):383-393(2023) [pubmed]

submitter keyword: Thermodynamics, thermal denaturation, chemical denaturation, protein folding

Michael C. Fitzgerald
contact affiliation	Professor of Chemistry Department of Chemistry Duke University
contact email	michael.c.fitzgerald@duke.edu
lab head
Morgan Bailey
contact affiliation	Duke University Department of Chemistry
contact email	morgan.a.bailey@duke.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/05/PXD036324

PRIDE project URI

• PRIDE
  1. PXD036324
     1. Label: PRIDE project
     2. Name: One-pot comparative analysis and characterization of young and old mice brain lysates