PXD036235

PXD036235 is an original dataset announced via ProteomeXchange.

Title	ANXA1 promotes tumor immune evasion by binding PARP1 and upregulating the transcription of PD-L1 in the multiple cancers
Description	To search proteins that interact with ANXA1, ANXA1 interactors were coimmunoprecipitated with anti-ANXA1 antibody from MB231 cell extracts, separated on SDS-PAGE and stained with Coomassie blue , and non-immune IgG antibody instead of anti-ANXA1 antibody served as control. All bands were excised, and subjected to in gel trypsin digestion and liquid chromatography and high-throughput mass spectrometry (LC-MS/MS) analysis.As a result, a total of 489 proteins including PARP1 were identified .
HostingRepository	iProX
AnnounceDate	2022-08-23
AnnouncementXML	Submission_2024-03-20_00:10:44.811.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Shanshan Lu
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2022-08-22 23:12:55	ID requested
⏵ 1	2024-03-20 00:10:45	announced

Xiao D, Zeng T, Zhu W, Yu ZZ, Huang W, Yi H, Lu SS, Feng J, Feng XP, Wu D, Wen Q, Zhou JH, Yuan L, Zhuang W, Xiao ZQ, ANXA1 Promotes Tumor Immune Evasion by Binding PARP1 and Upregulating Stat3-Induced Expression of PD-L1 in Multiple Cancers. Cancer Immunol Res, 11(10):1367-1383(2023) [pubmed]

submitter keyword: ANXA1, PARP1, PD-L1, cancerimmune evasion, cancer

Zhiqiang Xiao
contact affiliation	Research Center of Carcinogenesis and Targeted Therapy, Xiangya Hospital, Central South University
contact email	zqxiao2001@hotmail.com
lab head
Shanshan Lu
contact affiliation	Research Center of Carcinogenesis and Targeted Therapy, Xiangya Hospital, Central South University
contact email	susan880102@163.com
dataset submitter

iProX dataset URI