PXD036118

PXD036118 is an original dataset announced via ProteomeXchange.

Title	IKKβ binds NLRP3 providing a shortcut to inflammasome activation for rapid immune responses
Description	Quantitative proteomic profiling of TPCA-1-treated bone marrow-derived macrophages stimulated with TNF-α (50 ng/mL) for 24 h. TNF-α was used as an endogenous pro-inflammatory stimulus and inducer of sterile inflammation.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_08:36:55.026.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yaw Asare
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2022-08-16 14:10:03	ID requested
1	2023-03-10 20:20:11	announced
⏵ 2	2023-11-14 08:36:57	announced	2023-11-14: Updated project metadata.

Asare Y, Shnipova M, Ž, ivkovi, ć L, Schlegl C, Tosato F, Aronova A, Brandhofer M, Strohm L, Beaufort N, Malik R, Weber C, Bernhagen J, Dichgans M, binds NLRP3 providing a shortcut to inflammasome activation for rapid immune responses. Signal Transduct Target Ther, 7(1):355(2022) [pubmed]

submitter keyword: macrophages, TPCA-1, IKKβ, TNF-α

Martin Dichgans
contact affiliation	Institute for Stroke and Dementia Research (ISD), University Hospital, Ludwig-Maximilians-University (LMU) Munich, Munich, Germany
contact email	martin.dichgans@med.uni-muenchen.de
lab head
Yaw Asare
contact affiliation	Institute for Stroke and Dementia Research
contact email	yaw.asare@med.uni-muenchen.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/03/PXD036118

PRIDE project URI

• PRIDE
  1. PXD036118
     1. Label: PRIDE project
     2. Name: IKKβ binds NLRP3 providing a shortcut to inflammasome activation for rapid immune responses