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PXD035997

PXD035997 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleBrain phosphoproteomics in aging without AD
Description(Phospho)proteomic studies in the human aging brain are based on the comparison between controls of bain aging usually affected by early stages of neurofibrillary tangle (NFT) pathology and subjects with moderate or advanced Alzheimer’s disease (AD). (Phospho)proteomics using conventional label‐free‐ and SWATH‐MS (Sequential window acquisition of all theoretical fragment ion spectra mass spectrometry) has been assessed in the frontal cortex (FC) of individuals without NFTs and SPs, and comorbidities classified by age (years) in four groups; group 1 (young, 30-44); group 2 (middle-aged: MA, 45-52); group 3 (early-elderly, 64-70); and group 4 (late-elderly, 75-85).
HostingRepositoryjPOST
AnnounceDate2023-08-11
AnnouncementXMLSubmission_2023-08-10_08:00:06.030.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterEnrique Santamaría
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListS-carboxamidomethyl-L-cysteine; alpha-amino acetylated residue; L-methionine sulfoxide; O-phospho-L-serine; O-phospho-L-threonine; O4'-phospho-L-tyrosine
InstrumentTripleTOF 5600
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-08-12 03:15:05ID requested
12023-08-10 08:00:06announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: proteomics, brain, aging, frontal cortex
Contact List
isidro ferrer
lab head
Enrique Santamaría
contact affiliationNavarrabiomed
dataset submitter
Full Dataset Link List
jPOST dataset URI
Dataset FTP location
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