PXD035977 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Proteomic profiling of subsets of human primary NK cell-derived extracellular vesicles by LC-MS/MS |
Description | In this study we have compared the proteomic profile of subsets of extracellular vesicles (EVs) prepared from primary human NK cells cultured for 48hrs in serum-free conditions supplemented with 10 ng/ml human recombinant IL-12, IL-15, and IL-18. The aim was to isolate and define an EV subset with cytolytic activity against tumor cells. For this purpose, bulk EVs were separated according to density (density gradient ultracentrifugation; DG-UC) to yield 3 distinct subsets. |
HostingRepository | PRIDE |
AnnounceDate | 2023-11-14 |
AnnouncementXML | Submission_2023-11-14_08:57:13.791.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Tuula Nyman |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | timsTOF fleX |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-08-11 02:48:48 | ID requested | |
1 | 2022-09-09 05:24:20 | announced | |
⏵ 2 | 2023-11-14 08:57:14 | announced | 2023-11-14: Updated project metadata. |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: IL-18, NK cells,DG-UC, IL-12, IL-15, EVs, LC-MS/MS |
Contact List
Tuula Nyman |
contact affiliation | Head of Proteomics |
contact email | tuula.nyman@medisin.uio.no |
lab head | |
Tuula Nyman |
contact affiliation | University of Oslo |
contact email | tuula.nyman@medisin.uio.no |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD035977
- Label: PRIDE project
- Name: Proteomic profiling of subsets of human primary NK cell-derived extracellular vesicles by LC-MS/MS