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PXD035977

PXD035977 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomic profiling of subsets of human primary NK cell-derived extracellular vesicles by LC-MS/MS
DescriptionIn this study we have compared the proteomic profile of subsets of extracellular vesicles (EVs) prepared from primary human NK cells cultured for 48hrs in serum-free conditions supplemented with 10 ng/ml human recombinant IL-12, IL-15, and IL-18. The aim was to isolate and define an EV subset with cytolytic activity against tumor cells. For this purpose, bulk EVs were separated according to density (density gradient ultracentrifugation; DG-UC) to yield 3 distinct subsets.
HostingRepositoryPRIDE
AnnounceDate2023-11-14
AnnouncementXMLSubmission_2023-11-14_08:57:13.791.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterTuula Nyman
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumenttimsTOF fleX
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-08-11 02:48:48ID requested
12022-09-09 05:24:20announced
22023-11-14 08:57:14announced2023-11-14: Updated project metadata.
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: IL-18, NK cells,DG-UC, IL-12, IL-15, EVs, LC-MS/MS
Contact List
Tuula Nyman
contact affiliationHead of Proteomics
contact emailtuula.nyman@medisin.uio.no
lab head
Tuula Nyman
contact affiliationUniversity of Oslo
contact emailtuula.nyman@medisin.uio.no
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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