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PXD035809

PXD035809 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleBifidobacterium infantis utilizes N-acetylglucosamine nitrogen
Description15N-labeled N-acetylglucosamine (NAG) fed to B. infantis cells are incorporated into its proteome. This indicates that NAG, an amino sugar residue of human milk oligosaccharides (HMO) and other biopolymers, is used as a nitrogen source. Transcriptomics while subsisting on NAG nitrogen are consistent with the proteomics results. This further indicates that B. infantis utilizes NAG nitrogen in and shunts it towards a fundamental cellular processes.
HostingRepositoryPRIDE
AnnounceDate2023-05-18
AnnouncementXMLSubmission_2023-05-18_06:43:04.361.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterAshaRani
SpeciesList scientific name: Bacteria; NCBI TaxID: NCBITaxon:2; scientific name: Bifidobacterium longum subsp. infantis (strain ATCC 15697 / DSM 20088 / JCM 1222 / NCTC 11817 / S12); NCBI TaxID: 391904;
ModificationListacetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentOrbitrap Fusion
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-08-04 07:59:11ID requested
12023-05-18 06:43:04announced
Publication List
Dataset with its publication pending
Keyword List
ProteomeXchange project tag: Biology/Disease-Driven Human Proteome Project (B/D-HPP), Food and Nutrition (B/D-HPP), Human Proteome Project
submitter keyword: human milk oligosaccharides, N-acetyl glucosamine, 2-oxoglutarate, nitrogen metabolism,Bifidobacterium longum subsp. infantis
Contact List
David A.Sela
contact affiliationDavid A. Sela Associate Professor, Dept. of Food Science Adjunct Associate Professor, Dept. of Microbiology University of Massachusetts Amherst Adjunct Associate Professor, Dept. of Microbiology & Physiological Systems University of Massachusetts Medical School selalab.org 413.545.1010
contact emaildavidsela@umass.edu
lab head
AshaRani
contact affiliationUniversity of Massachusetts Amherst
contact emailarani@umass.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
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