PXD035807

PXD035807 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Proteome of Mycobacterium tuberculosis treated with 2,4-disubstituted pyridine derivatives
Description	Two selected compounds, 2,4-disubstituted pyridine derivatives (11 and 15), revealed significant bactericidal activity against Mycobacterium tuberculosis deposited within human macrophages as well as against biofilm-forming tubercle bacilli. The mass spectrometry-based proteomics (LC-MS/MS) of the wild-type tubercle bacilli growing in the subinhibitory concentration of 11 or 15 revealed 15 overproduced proteins not detectable in the control cells including virulence-related proteins.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_08:57:09.819.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Przemyslaw Plocinski
SpeciesList	scientific name: Mycobacterium tuberculosis H37Rv; NCBI TaxID: 83332;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2022-08-04 07:58:04	ID requested
1	2022-11-02 04:35:46	announced
⏵ 2	2023-11-14 08:57:10	announced	2023-11-14: Updated project metadata.

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: Mycobacterium tuberculosis, antimicrobials

submitter keyword: Mycobacterium tuberculosis, antimicrobials

Contact List

Jaroslaw Dziadek
contact affiliation	Laboratory of Genetics and Physiology of Mycobacterium, Institute of Medical Biology of the Polish Academy of Sciences, Lodz, Poland
contact email	jdziadek@cbm.pan.pl
lab head
Przemyslaw Plocinski
contact affiliation	Institute of Medical Biology of the Polish Academy of Sciences
contact email	przemyslaw.plocinski@gmail.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/11/PXD035807
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/11/PXD035807

PRIDE project URI

Repository Record List

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