PXD035723 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Molecular basis for differential activation of p101 and p84 complexes of PI3Kg by Ras and GPCRs |
Description | Using hydrogen deuterium exchange mass spectrometry, we reveal molecular differences between the two p110g-p84 and p110g-p101 complexes that explain their differential activation. |
HostingRepository | PRIDE |
AnnounceDate | 2023-11-14 |
AnnouncementXML | Submission_2023-11-14_08:25:22.012.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | John Burke |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | impact HD |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-08-02 02:18:49 | ID requested | |
1 | 2023-03-09 17:52:28 | announced | |
⏵ 2 | 2023-11-14 08:25:22 | announced | 2023-11-14: Updated project metadata. |
Publication List
Rathinaswamy MK, Jenkins ML, Duewell BR, Zhang X, Harris NJ, Evans JT, Stariha JTB, Dalwadi U, Fleming KD, Ranga-Prasad H, Yip CK, Williams RL, Hansen SD, Burke JE, by Ras and GPCRs. Cell Rep, 42(3):112172(2023) [pubmed] |
Keyword List
submitter keyword: pi3kg, p101, ras, p110g, HDX-MS,HDX, gby |
Contact List
John Burke |
contact affiliation | University of Victoria |
contact email | jeburke@uvic.ca |
lab head | |
John Burke |
contact affiliation | University of Victoria |
contact email | jeburke@uvic.ca |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/03/PXD035723 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD035723
- Label: PRIDE project
- Name: Molecular basis for differential activation of p101 and p84 complexes of PI3Kg by Ras and GPCRs