PXD035655

PXD035655 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Tear protein profile in eyes with keratoconus after one year of intrastromal corneal ring and corneal crosslinking: a pilot study
Description	Keratoconus (KC) is a corneal ectasia characterized by structural changes, resulting in progressive thinning and biomechanical weakening that can lead to worsening visual acuity due to irregular astigmatism. Corneal collagen Crosslinking (CXL) and Intracorneal Ring Segment (ICRS) are widely used treatments in KC disease, but the alterations they cause in biomechanical mediators are still poorly understood. The aim of this study was to analyze the tear proteome profile before and after treatments to identify biomarkers altered by surgery.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_07:32:36.393.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD035655
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Mikel Azkargorta
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF Pro

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2022-08-01 01:57:48	ID requested
1	2022-11-29 04:22:18	announced
⏵ 2	2023-11-14 07:32:37	announced	2023-11-14: Updated project metadata.

Publication List

Go, ñ, i N, Mart, í, nez-Soroa I, Ibarrondo O, Azkargorta M, Elortza F, Galarreta DJ, Acera A, Tear proteome profile in eyes with keratoconus after intracorneal ring segment implantation or corneal crosslinking. Front Med (Lausanne), 9():944504(2022) [pubmed]
10.6019/PXD035655;

Go, ñ, i N, Mart, í, nez-Soroa I, Ibarrondo O, Azkargorta M, Elortza F, Galarreta DJ, Acera A, Tear proteome profile in eyes with keratoconus after intracorneal ring segment implantation or corneal crosslinking. Front Med (Lausanne), 9():944504(2022) [pubmed]

10.6019/PXD035655;

Keyword List

submitter keyword: Keratoconus, Intracorneal Ring Segment, Crosslinking, tear film

submitter keyword: Keratoconus, Intracorneal Ring Segment, Crosslinking, tear film

Contact List

Felix Elortza
contact affiliation	Proteomics Service CIC bioGUNE Bizkaia Tech. Park Build. 800 Derio (48160) Spain
contact email	felortza@cicbiogune.es
lab head
Mikel Azkargorta
contact affiliation	Proteomics Platform CIC bioGUNE
contact email	mazkargorta@cicbiogune.es
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/10/PXD035655
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/10/PXD035655

PRIDE project URI

Repository Record List

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