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PXD035618

PXD035618 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleInsights into the digestive gland of Mytilus coruscus under heat stress using TMT-based proteomics
DescriptionA healthy existence relationship between mussels and environment relies on suitable PH, adequate oxygen and suitable temperature. Besides ocean acidification, ocean warming has been shown to cause mussel dead, a phenomenon responsible for extensive mussel dead around the word. How heat stress impacts mussel alive is poorly understood. We founded that. The superoxide dismutase (SOD) activity of two treatment groups were significantly higher than that of control group, and the activity of acid phosphatase (ACP) was significantly higher in two treatment groups than control group. The lactate dehydrogenase (LDH) activity of 26 ℃ treatment group was significantly higher than that of control group, and the LDH activity of 33 ℃ treatment group was significantly lower than that of control group. Cellular content of lysozyme (LZM) was significantly higher in two treatment groups than control group. In this study, we applied TMT quantification to investigate how Mytilus coruscus responds to heat stress (26 ℃, 33 ℃). We identified 1652 to 1878 differentially expressed proteins (DEPs) from these heat conditions, among which 897 were commonly regulated by all the two temperature and were significantly enriched in nutrients digestion and absorption (e. g. fat digestion and absorption). Furthermore, proteins associated with nutrients metabolism, signaling pathways (p53 signaling pathway and MAPK signaling pathway)and energy metabolism (e. g. TCA cycle) were impacted, suggesting that the ability of basic metabolism of Mytilus coruscus may be altered by heat stress.
HostingRepositoryPRIDE
AnnounceDate2023-05-30
AnnouncementXMLSubmission_2023-05-30_01:04:19.765.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitter乐钟许
SpeciesList scientific name: Mytilus coruscus; NCBI TaxID: 42192;
ModificationListTMT6plex-126 reporter+balance reagent acylated residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-07-29 06:55:45ID requested
12023-05-30 01:04:20announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: heat stress,Mytlius coruscus,TMT
Contact List
Insights into the digestive gland of Mytilus coruscus under heat stress using TMT-basedproteomics
contact affiliationZhejiang Ocean University
contact email3454606890@qq.com
lab head
乐钟许
contact affiliation19883838836
contact email3454606890@qq.com
dataset submitter
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Dataset FTP location
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