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PXD035614

PXD035614 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleMutated in Colorectal Cancer (MCC): A Novel Centrosomal Protein Involved in Intestinal Homeostasis and Disease
DescriptionMutated in Colorectal Cancer (MCC) is a candidate tumor suppressor gene reported to be somatically mutated in the inherited colorectal cancer (CRC) syndrome Familial Adenomatous Polyposis. Additionally, MCC deletion and loss-ofheterozygosity have also been reported as a common event in human CRC. However,to date, more than 28 years since its discovery, the mechanisms by which MCC contributes to intestinal cancer development as well as its function during normal intestinal tissue homeostasis remain unknown.
HostingRepositoryjPOST
AnnounceDate2023-07-29
AnnouncementXMLSubmission_2023-07-28_08:00:05.736.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterRadoslaw Sobota
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListS-carboxamidomethyl-L-cysteine; L-methionine sulfoxide; alpha-amino acetylated residue; deamidated L-glutamine; deamidated L-asparagine
Instrumentinstrument
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-07-29 01:32:31ID requested
12023-07-28 08:00:06announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: MCC, Centrosome, Colorectal Cancer
Contact List
Ray Dunn
lab head
Radoslaw Sobota
contact affiliationIMCB A-STAR Singapore
dataset submitter
Full Dataset Link List
jPOST dataset URI
Dataset FTP location
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