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PXD035613

PXD035613 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleChronic high glucose condition reduced expressions of intercellular adhesion molecules and increased intercellular hyperpermeability in periodontal epithelium.
DescriptionThere is a close relationship between hyperglycemia in diabetes and progression of periodontal disease. This study aims to investigate the effect of hyperglycemia on the barrier function of gingival epithelial cells as a cause of hyperglycemia-exacerbated periodontitis in diabetes mellitus. Abnormal expressions of adhesion molecules in gingival epithelium in diabetes were compared between db⁄db and control mice.
HostingRepositoryjPOST
AnnounceDate2023-07-29
AnnouncementXMLSubmission_2023-12-24_21:46:30.916.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterNaoyuki Sugiyama
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListS-carboxamidomethyl-L-cysteine; L-methionine sulfoxide; TMT6plex reporter+balance reagent acylated N-terminal; TMT6plex reporter+balance reagent N-acylated residue
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-07-28 21:57:59ID requested
12023-07-28 08:00:16announced
22023-12-24 21:46:31announced2023-12-25: Updated PubMed.
Publication List
Narukawa Y, Sugiyama N, Miura J, Yamashita R, Tominaga S, Izumi Y, Bamba T, Ishihama Y, Kashiwagi Y, Murakami S, Chronic hyperglycemia reduces the expression of intercellular adhesion molecules and increases intercellular hyperpermeability in the periodontal epithelium. J Periodontal Res, 58(4):813-826(2023) [pubmed]
Keyword List
submitter keyword: rat gingival tissues
Contact List
Yoichiro Kashiwagi
lab head
Naoyuki Sugiyama
contact affiliationKyoto University
dataset submitter
Full Dataset Link List
jPOST dataset URI
Dataset FTP location
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