PXD035613

PXD035613 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Chronic high glucose condition reduced expressions of intercellular adhesion molecules and increased intercellular hyperpermeability in periodontal epithelium.
Description	There is a close relationship between hyperglycemia in diabetes and progression of periodontal disease. This study aims to investigate the effect of hyperglycemia on the barrier function of gingival epithelial cells as a cause of hyperglycemia-exacerbated periodontitis in diabetes mellitus. Abnormal expressions of adhesion molecules in gingival epithelium in diabetes were compared between db⁄db and control mice.
HostingRepository	jPOST
AnnounceDate	2023-07-29
AnnouncementXML	Submission_2023-12-24_21:46:30.916.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Naoyuki Sugiyama
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	S-carboxamidomethyl-L-cysteine; L-methionine sulfoxide; TMT6plex reporter+balance reagent acylated N-terminal; TMT6plex reporter+balance reagent N-acylated residue
Instrument	Orbitrap Fusion Lumos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2022-07-28 21:57:59	ID requested
1	2023-07-28 08:00:16	announced
⏵ 2	2023-12-24 21:46:31	announced	2023-12-25: Updated PubMed.

Publication List

Narukawa Y, Sugiyama N, Miura J, Yamashita R, Tominaga S, Izumi Y, Bamba T, Ishihama Y, Kashiwagi Y, Murakami S, Chronic hyperglycemia reduces the expression of intercellular adhesion molecules and increases intercellular hyperpermeability in the periodontal epithelium. J Periodontal Res, 58(4):813-826(2023) [pubmed]

Narukawa Y, Sugiyama N, Miura J, Yamashita R, Tominaga S, Izumi Y, Bamba T, Ishihama Y, Kashiwagi Y, Murakami S, Chronic hyperglycemia reduces the expression of intercellular adhesion molecules and increases intercellular hyperpermeability in the periodontal epithelium. J Periodontal Res, 58(4):813-826(2023) [pubmed]

Keyword List

submitter keyword: rat gingival tissues

submitter keyword: rat gingival tissues

Contact List

Yoichiro Kashiwagi
lab head
Naoyuki Sugiyama
contact affiliation	Kyoto University
dataset submitter

Full Dataset Link List

jPOST dataset URI
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jPOST dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST001800/