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PXD035529

PXD035529 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleHuman Cardiovascular Tissue Extracellular Vesicles
DescriptionFewer than 50% of patients develop vascular and valvular calcification, implying differential pathogenesis. Tissue-entrapped extracellular vesicles (EVs) are found in mineralization but their contents and functions are unstudied. Tissue EVs were isolated from normal and diseased human carotid arteries and aortic valves by enzymatic digestion, serial (ultra)centrifugation and density-gradient separation.
HostingRepositoryPRIDE
AnnounceDate2023-11-14
AnnouncementXMLSubmission_2023-11-14_07:06:26.435.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD035529
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterMark Blaser
SpeciesList scientific name: HATHI; NCBI TaxID: 1498; scientific name: Homo sapiens (Human); NCBI TaxID: 9606; scientific name: Hathewaya proteolytica; NCBI TaxID: 29365;
ModificationListL-methionine sulfoxide; acetylated residue; iodoacetamide derivatized residue
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-07-24 04:56:07ID requested
12023-07-10 09:10:56announced
22023-11-14 07:06:26announced2023-11-14: Updated project metadata.
Publication List
10.6019/PXD035529;
Keyword List
submitter keyword: Human, LC-MSMS, extracellular vesicle, exosome, calcification, aortic valve, carotid endarterectomy, atherosclerotic plaque
Contact List
Elena Aikawa
contact affiliationBrigham and Women's Hospital, Harvard Medical School
contact emaileaikawa@bwh.harvard.edu
lab head
Mark Blaser
contact affiliationBrigham and Women's Hospital, Harvard Medical School
contact emailmblaser@bwh.harvard.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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