PXD035527

PXD035527 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	HNSCC-derived factors promote fibroblast invasion
Description	MS-based phosphoproteomic analysis was performed to investigate rapid and specific changes in the phosphorylation status and kinase activation in CAFs upon treatment with HNSCC CM (from FaDu and HCA-LSC1 cells) or Kc CM. Comparisons of phosphorylation levels were conducted at two different time points (15 minutes and 1 hour) using three different biological replicates for each condition assayed
HostingRepository	PRIDE
AnnounceDate	2025-07-21
AnnouncementXML	Submission_2025-07-21_07:28:10.579.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD035527
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Vinothini Rajeeve
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	phosphorylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2022-07-24 04:52:57	ID requested
⏵ 1	2025-07-21 07:28:10	announced

Publication List

10.6019/PXD035527;

10.6019/PXD035527;

Keyword List

submitter keyword: cancer-associated fibroblasts, stromal fibroblasts,Head and neck cancer, Invasion, phosphoproteomics

submitter keyword: cancer-associated fibroblasts, stromal fibroblasts,Head and neck cancer, Invasion, phosphoproteomics

Contact List

Pedro R. Cutillas
contact affiliation	Professor of Cell Signalling & Proteomics Centre for Genomics and Computational Biology Barts Cancer Institute Queen Mary, University of London John Vane Science Centre, Charterhouse Square, London EC1M 6BQ
contact email	p.cutillas@qmul.ac.uk
lab head
Vinothini Rajeeve
contact affiliation	Centre for Haemato Oncology
contact email	v.rajeeve@qmul.ac.uk
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/07/PXD035527
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/07/PXD035527

PRIDE project URI

Repository Record List

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