Update information. We enrolled 37 SARS-CoV-2 positive patients including 17 short course (SC) COVID-19 patients (twice viral RNA detection negative over 24 hrs) and 20 COVID-19 long course (LC) COVID-19 patients. We also included 35 SARS-CoV-2 negative patients as control group. We collected 224 inactive serum samples from this cohort and their clinical data. For those Covid-19 patients, we included 37 patients with 2-9 weeks comparing with negative control patients and used tandem mass tag (TMT) based proteomics method to profile temporal proteomics change for this cohort.