PXD035456

PXD035456 is an original dataset announced via ProteomeXchange.

Title	Rapid Detection of Procalcitonin in septic serum by Immunoaffinity MALDI Chips
Description	PCT concentration in the bloodstream correlates well with sepsis presence and in severe cases increases up to a thousand times from the healthy physiological values in a short time. In this study, we developed a rapid technique for PCT detection by MALDI-MS, that uses in-situ enrichment directly on the specialized immuno MALDI chips that are utilized directly as MALDI plates. The method’s ability to detect PCT was confirmed by comparing the results with LC-MS bottom-up workflow.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:54:38.576.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Petr Pompach
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	maXis

Revision	Datetime	Status	ChangeLog Entry
0	2022-07-20 05:36:50	ID requested
1	2023-07-20 10:43:57	announced
2	2023-11-14 09:02:39	announced	2023-11-14: Updated project metadata.
⏵ 3	2024-10-22 05:54:39	announced	2024-10-22: Updated project metadata.

10.1186/s12014-023-09410-3;

Dvorak J, Novakova J, Kraftova L, Studentova V, Matejovic M, Radej J, Karvunidis T, Horak J, Kralovcova M, Hrabak J, Kalaninova Z, Volny M, Novak P, Pompach P, The rapid detection of procalcitonin in septic serum using immunoaffinity MALDI chips. Clin Proteomics, 20(1):20(2023) [pubmed]

submitter keyword: immunoaffinity chips,Procalcitonin, MALDI-TOF, sepsis

Petr Pompach
contact affiliation	Institute of Biotechnology, Czech Republic
contact email	petr.pompach@ibt.cas.cz
lab head
Petr Pompach
contact affiliation	Intitute of Biotechnology
contact email	petr.pompach@ibt.cas.cz
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/07/PXD035456

PRIDE project URI

• PRIDE
  1. PXD035456
     1. Label: PRIDE project
     2. Name: Rapid Detection of Procalcitonin in septic serum by Immunoaffinity MALDI Chips