PXD035366

PXD035366 is an original dataset announced via ProteomeXchange.

Title	Screening and identification of hair follicle initiation and development related gene in the fetal period of Inner Mongolian Cashmere Goat
Description	Cashmere is an important economic product in Cashmere goat farming. The value of cashmere fleece is thought to be determined by the numbers and density of HFs. In recent years, molecular mechanisms that govern HF cyclic regeneration have been revealed in Cashmere goat breeds, but molecular mechanisms that govern HF initiation, growth and development process in the fetal period is relatively scarce. At present, life science has entered into the Post-Genome Era, the transcriptome and proteomics are important contents of functional genomics research, and also provide useful ways for further study on functional mechanism of hair follicle growth and development. In our study, skin samples at 10 different fetal periods were collected from the lateral body of each Cashmere goat. The RNA-seq and ITRAQ at three specific developmental stages: 45- , 55- and 65-day-old fetuses (E45, E55 and E65) were carried out in the present study according to the preliminary results, the results of sequencing were verified by qPCR and Western blotting (WB) respectively. In order to enhance our understanding of the molecular regulation mechanism and provides research foundation for cashmere HF initiation and development, we carried out omics conjoint analysis
HostingRepository	iProX
AnnounceDate	2022-07-14
AnnouncementXML	Submission_2022-07-17_19:42:44.484.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Lele Wang
SpeciesList	scientific name: Capra hircus; NCBI TaxID: 9925;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2022-07-17 19:42:32	ID requested
⏵ 1	2022-07-17 19:42:44	announced

Dataset with its publication pending

submitter keyword: Cashmere goat fetuses, skin hair follicle, proteomics, ITRAQ transcriptome sequencing，Omics conjoint analysis, gene screening，functional identification

Yanjun Zhang
contact affiliation	Ulanqab of medical college, College of Animal Science, Inner Mongolia Agricultural University
contact email	imauzyj@163.com
lab head
Lele Wang
contact affiliation	Ulanqab of medical college, College of Animal Science, Inner Mongolia Agricultural University
contact email	leleruwu@sina.cn
dataset submitter

iProX dataset URI