PXD035352 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Complexome profiling of testis tissue in WT and ClpP-/- mice |
Description | Mutations in the gene for the mitochondrial matrix protease CLPP can cause human Perrault syndrome, which is characterized by male and female infertility, progressive sensorineural deafness, ataxia and leukoencephalopathy. This gene encodes a peptidase that is conserved since bacteria and localizes to mitochondrial matrix in eukaryotes. To assess the assembly and stability of mitochondrial complexes testes of WT and ClpP-/- mice were dissected and enriched mitochondrial fraction was used for complexome profiling. |
HostingRepository | PRIDE |
AnnounceDate | 2024-01-17 |
AnnouncementXML | Submission_2024-01-17_05:49:35.971.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Jana Key |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | iodoacetamide derivatized residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-07-14 08:16:21 | ID requested | |
⏵ 1 | 2024-01-17 05:49:36 | announced | |
Publication List
Keyword List
submitter keyword: Protease function, Complexome profiling |
Contact List
Georg Auburger |
contact affiliation | Experimental Neurology, University Hospital, Frankfurt am Main, Germany |
contact email | auburger@em.uni-frankfurt.de |
lab head | |
Jana Key |
contact affiliation | University Hospital Frankfurt am Main |
contact email | jana.key88@gmail.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD035352
- Label: PRIDE project
- Name: Complexome profiling of testis tissue in WT and ClpP-/- mice