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PXD035255

PXD035255 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleMouse Liver LC-MS/MS Analysis Following Treatment With Lifespan-Extending Drugs
DescriptionAging manifests as progressive deterioration in cellular and systemic homeostasis, requiring systems-level perspectives to understand the gradual molecular dysregulation of underlying biological processes. Here, we collected data for the analysis of systems-level changes in the molecular regulation of biological processes under multiple lifespan-extending interventions in mice. High-resolution shotgun LC-MS/MS data were collected from liver samples obtained from multiple mouse cohorts treated with different lifespan-extending drugs, and analyzed using reverse phase liquid chromatography on Orbitrap mass spectrometers.
HostingRepositoryPRIDE
AnnounceDate2023-11-14
AnnouncementXMLSubmission_2023-11-14_06:42:26.404.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD035255
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterMichael Hoopmann
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive HF; Orbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-07-11 13:51:46ID requested
12023-07-25 01:02:13announced
22023-11-14 06:42:26announced2023-11-14: Updated project metadata.
Publication List
10.6019/PXD035255;
Keyword List
submitter keyword: Mouse, Shotgun MS/MS, Liver, Orbitrap, Lifespan
Contact List
Robert L. Moritz
contact affiliationInstitute for Systems Biology
contact emailrmoritz@systemsbiology.org
lab head
Michael Hoopmann
contact affiliationInstitute for Systems Biology
contact emailmichael.hoopmann@systemsbiology.org
dataset submitter
Full Dataset Link List
Dataset FTP location
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