PXD035255 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Mouse Liver LC-MS/MS Analysis Following Treatment With Lifespan-Extending Drugs |
Description | Aging manifests as progressive deterioration in cellular and systemic homeostasis, requiring systems-level perspectives to understand the gradual molecular dysregulation of underlying biological processes. Here, we collected data for the analysis of systems-level changes in the molecular regulation of biological processes under multiple lifespan-extending interventions in mice. High-resolution shotgun LC-MS/MS data were collected from liver samples obtained from multiple mouse cohorts treated with different lifespan-extending drugs, and analyzed using reverse phase liquid chromatography on Orbitrap mass spectrometers. |
HostingRepository | PRIDE |
AnnounceDate | 2023-11-14 |
AnnouncementXML | Submission_2023-11-14_06:42:26.404.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD035255 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Michael Hoopmann |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive HF; Orbitrap Fusion Lumos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-07-11 13:51:46 | ID requested | |
1 | 2023-07-25 01:02:13 | announced | |
⏵ 2 | 2023-11-14 06:42:26 | announced | 2023-11-14: Updated project metadata. |
Publication List
Keyword List
submitter keyword: Mouse, Shotgun MS/MS, Liver, Orbitrap, Lifespan |
Contact List
Robert L. Moritz |
contact affiliation | Institute for Systems Biology |
contact email | rmoritz@systemsbiology.org |
lab head | |
Michael Hoopmann |
contact affiliation | Institute for Systems Biology |
contact email | michael.hoopmann@systemsbiology.org |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD035255
- Label: PRIDE project
- Name: Mouse Liver LC-MS/MS Analysis Following Treatment With Lifespan-Extending Drugs