PXD035236

PXD035236 is an original dataset announced via ProteomeXchange.

Title	NUPR1 inhibits hyperPARylation-associated cell death
Description	Nuclear Protein 1 (NUPR1) is a nuclear intrinsically disordered protein of 82 amino acids that plays an important role in stress response and in cancer development. The project was aimed at identifying binding partners of NUPR1 in MiaPaCa-2 cells, in control and after stress condition: glucose starvation during 24h. Lysates from MiaPaCa-2 cells (transfected with NUPR1-Flag or NUPR1-GFP) were used for immunoprecipitation, performed with agarose beads coated with anti-Flag or anti-GFP antibodies. After immunoprecipitation, the eluted proteins were analyzed by LC-MS/MS.
HostingRepository	PRIDE
AnnounceDate	2022-07-29
AnnouncementXML	Submission_2022-07-29_04:56:52.331.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	AUDEBERT Stephane
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive Plus

Revision	Datetime	Status	ChangeLog Entry
0	2022-07-11 08:27:02	ID requested
⏵ 1	2022-07-29 04:56:53	announced

Santofimia-Casta, ñ, o P, Huang C, Liu X, Xia Y, Audebert S, Camoin L, Peng L, Lomberk G, Urrutia R, Soubeyran P, Neira JL, Iovanna J, NUPR1 protects against hyperPARylation-dependent cell death. Commun Biol, 5(1):732(2022) [pubmed]

submitter keyword: Pancreatic cancer, NUPR1, LC-MSMS, Interactome

Dr. Santofimia Patricia
contact affiliation	Centre de Recherche en Cancérologie de Marseille, CRCM INSERM U1068 - Equipe de J.L. Iovanna 163 avenue de Luminy, Parc scientifique de Luminy, Case 915 13288 Marseille Cedex 9 FRANCE Tel : (+33) 4 91 82 88 31
contact email	patricia.santofimia@inserm.fr
lab head
AUDEBERT Stephane
contact affiliation	Marseille Proteomic, Centre de Recherche en Cancérologie de Marseille, Inserm UMR1068, CNRS UMR7258, Aix Marseille Université U105, Institut Paoli Calmettes, 27 Boulevard Leï Roure CS30059 13273 Marseille Cedex 09 France
contact email	stephane.audebert@inserm.fr
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/07/PXD035236

PRIDE project URI

• PRIDE
  1. PXD035236
     1. Label: PRIDE project
     2. Name: NUPR1 inhibits hyperPARylation-associated cell death