PXD035236 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | NUPR1 inhibits hyperPARylation-associated cell death |
Description | Nuclear Protein 1 (NUPR1) is a nuclear intrinsically disordered protein of 82 amino acids that plays an important role in stress response and in cancer development. The project was aimed at identifying binding partners of NUPR1 in MiaPaCa-2 cells, in control and after stress condition: glucose starvation during 24h. Lysates from MiaPaCa-2 cells (transfected with NUPR1-Flag or NUPR1-GFP) were used for immunoprecipitation, performed with agarose beads coated with anti-Flag or anti-GFP antibodies. After immunoprecipitation, the eluted proteins were analyzed by LC-MS/MS. |
HostingRepository | PRIDE |
AnnounceDate | 2022-07-29 |
AnnouncementXML | Submission_2022-07-29_04:56:52.331.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | AUDEBERT Stephane |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive Plus |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-07-11 08:27:02 | ID requested | |
⏵ 1 | 2022-07-29 04:56:53 | announced | |
Publication List
Santofimia-Casta, ñ, o P, Huang C, Liu X, Xia Y, Audebert S, Camoin L, Peng L, Lomberk G, Urrutia R, Soubeyran P, Neira JL, Iovanna J, NUPR1 protects against hyperPARylation-dependent cell death. Commun Biol, 5(1):732(2022) [pubmed] |
Keyword List
submitter keyword: Pancreatic cancer, NUPR1, LC-MSMS, Interactome |
Contact List
Dr. Santofimia Patricia |
contact affiliation | Centre de Recherche en Cancérologie de Marseille, CRCM INSERM U1068 - Equipe de J.L. Iovanna 163 avenue de Luminy, Parc scientifique de Luminy, Case 915 13288 Marseille Cedex 9 FRANCE Tel : (+33) 4 91 82 88 31 |
contact email | patricia.santofimia@inserm.fr |
lab head | |
AUDEBERT Stephane |
contact affiliation | Marseille Proteomic, Centre de Recherche en Cancérologie de Marseille, Inserm UMR1068, CNRS UMR7258, Aix Marseille Université U105, Institut Paoli Calmettes, 27 Boulevard Leï Roure CS30059 13273 Marseille Cedex 09 France |
contact email | stephane.audebert@inserm.fr |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD035236
- Label: PRIDE project
- Name: NUPR1 inhibits hyperPARylation-associated cell death