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PXD035236

PXD035236 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleNUPR1 inhibits hyperPARylation-associated cell death
DescriptionNuclear Protein 1 (NUPR1) is a nuclear intrinsically disordered protein of 82 amino acids that plays an important role in stress response and in cancer development. The project was aimed at identifying binding partners of NUPR1 in MiaPaCa-2 cells, in control and after stress condition: glucose starvation during 24h. Lysates from MiaPaCa-2 cells (transfected with NUPR1-Flag or NUPR1-GFP) were used for immunoprecipitation, performed with agarose beads coated with anti-Flag or anti-GFP antibodies. After immunoprecipitation, the eluted proteins were analyzed by LC-MS/MS.
HostingRepositoryPRIDE
AnnounceDate2022-07-29
AnnouncementXMLSubmission_2022-07-29_04:56:52.331.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterAUDEBERT Stephane
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive Plus
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-07-11 08:27:02ID requested
12022-07-29 04:56:53announced
Publication List
Santofimia-Casta, ñ, o P, Huang C, Liu X, Xia Y, Audebert S, Camoin L, Peng L, Lomberk G, Urrutia R, Soubeyran P, Neira JL, Iovanna J, NUPR1 protects against hyperPARylation-dependent cell death. Commun Biol, 5(1):732(2022) [pubmed]
Keyword List
submitter keyword: Pancreatic cancer, NUPR1, LC-MSMS, Interactome
Contact List
Dr. Santofimia Patricia
contact affiliationCentre de Recherche en Cancérologie de Marseille, CRCM INSERM U1068 - Equipe de J.L. Iovanna 163 avenue de Luminy, Parc scientifique de Luminy, Case 915 13288 Marseille Cedex 9 FRANCE Tel : (+33) 4 91 82 88 31
contact emailpatricia.santofimia@inserm.fr
lab head
AUDEBERT Stephane
contact affiliationMarseille Proteomic, Centre de Recherche en Cancérologie de Marseille, Inserm UMR1068, CNRS UMR7258, Aix Marseille Université U105, Institut Paoli Calmettes, 27 Boulevard Leï Roure CS30059 13273 Marseille Cedex 09 France
contact emailstephane.audebert@inserm.fr
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
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