PXD035173 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Proteomic profiling of carotid atherosclerotic plaques and adjacent intact arterial segments |
Description | Although it is well known that the extracellular matrix composition significantly impacts the development of neointimal hyperplasia and atherosclerosis, the biochemical cues regulating the cell-ECM interactions within the neointima remain obscure. Here, we pairwise collected 14 atherosclerotic plaques excised during the carotid endarterectomy and 14 adjacent intact aortic segments and then interrogated their proteomic profile. |
HostingRepository | PRIDE |
AnnounceDate | 2025-06-05 |
AnnouncementXML | Submission_2025-06-05_00:33:42.189.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Arseniy Lobov |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | acetylated residue; monohydroxylated residue; deaminated residue; iodoacetamide derivatized residue |
Instrument | timsTOF Pro |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-07-08 01:26:13 | ID requested | |
⏵ 1 | 2025-06-05 00:33:43 | announced | |
Publication List
Kanonykina A, Velikanova E, Markova V, Bogdanov L, Shishkova D, Shabaev A, Sinitsky M, Sinitskaya A, Poddubnyak A, Lazebnaya A, Stepanov A, Tyurina A, Lobov A, Zainullina B, Yuzhalin A, Kutikhin A, Citrullination Accompanies the Development of Carotid Atherosclerotic Plaques. Curr Med Chem, ():(2024) [pubmed] |
10.2174/0109298673327175240929222308; |
Keyword List
submitter keyword: atherosclerosis, TimsToF Pro, diaPASEF, data-independent acquisition |
Contact List
Anton G. Kutikhin |
contact affiliation | Laboratory of Molecular, Translational and Digital Medicine, Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo, Russia |
contact email | antonkutikhin@gmail.com |
lab head | |
Arseniy Lobov |
contact affiliation | Yifat Merbl Lab, Dept. of Systems Immunology, Weizmann Institute of Science |
contact email | arseniylobov@gmail.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/06/PXD035173 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD035173
- Label: PRIDE project
- Name: Proteomic profiling of carotid atherosclerotic plaques and adjacent intact arterial segments