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PXD035146

PXD035146 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleInteractome of ferroptosis pathways genes
DescriptionWe conducted a proteomic interactome analysis of well-known regulators of ferroptosis, ACSL4, LPCAT3, ALOX12, ALOX15, PEBP1, NCOA4, GCH1, FSP1, DHODH, SLC7A11, GCLC, GCLM, GSS, and GPX4. Take LPCAT3 as an example, we uncovered an opposing role of its binding protein CEPT1 in suppressing ferroptosis.
HostingRepositoryPRIDE
AnnounceDate2024-10-17
AnnouncementXMLSubmission_2024-10-17_03:00:10.886.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterZhen Chen
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-07-07 01:02:29ID requested
12024-10-17 03:00:11announced
Publication List
10.1093/procel/pwae004;
Liu X, Chen Z, Yan Y, Zandkarimi F, Nie L, Li Q, Horbath A, Olszewski K, Kondiparthi L, Mao C, Lee H, Zhuang L, Poyurovsky M, Stockwell BR, Chen J, Gan B, Proteomic analysis of ferroptosis pathways reveals a role of CEPT1 in suppressing ferroptosis. Protein Cell, 15(9):686-703(2024) [pubmed]
Keyword List
submitter keyword: ferroptosis, TAP-MS, interactome
Contact List
Junjie Chen
contact affiliationDepartment of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center
contact emailjchen8@mdanderson.org
lab head
Zhen Chen
contact affiliationThe University of Texas MD Anderson Cancer Center
contact emailzchen6@mdanderson.org
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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