PXD035132
PXD035132 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Integrated Analysis of Proteomics and Metabolomics in Girls with Central Precocious Puberty |
| Description | Central precocious puberty (CPP) is a multifactorial and complex condition. Traditional studies focusing on a single indicator cannot always elucidate this panoramic condition but these may be revealed by using omics techniques. Proteomics and metabolomics analysis of girls with CPP were compared to normal controls and the potential biomarkers and pathways involved were explored. Serum proteins and metabolites from normal girls and those with CPP were compared by LC-MS/MS. Multivariate and univariate statistical analysis were used to identify the differentially expressed proteins (DEPs) and differentially expressed metabolites (DEMs). Functional annotation and pathway enrichment analysis were performed by using GO and KEGG databases, and candidate markers were screened. Finally, bioinformatic analysis was used to integrate the results of proteomics and metabolomics to find the key differential proteins, metabolites and potential biomarkers of CPP. |
| HostingRepository | iProX |
| AnnounceDate | 2022-07-06 |
| AnnouncementXML | Submission_2022-08-24_23:49:23.868.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Mei Li |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | timsTOF Pro |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2022-07-06 19:29:59 | ID requested | |
| 1 | 2022-07-14 02:27:30 | announced | |
| ⏵ 2 | 2022-08-24 23:49:24 | announced | 2022-08-25: Update information. |
Publication List
| Li M, Lan D, Chen Y, Integrated analysis of proteomics and metabolomics in girls with central precocious puberty. Front Endocrinol (Lausanne), 13():951552(2022) [pubmed] |
Keyword List
| submitter keyword: Proteomics, Metabolomics, Central Precocious Puberty |
Contact List
| Dan Lan | |
|---|---|
| contact affiliation | The First Affiliated Hospital of Guangxi Medical University |
| contact email | landan_ld@163.com |
| lab head | |
| Mei Li | |
| contact affiliation | The First Affiliated Hospital of Guangxi Medical University |
| contact email | m13978842566@163.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
to receive all new ProteomeXchange dataset release announcements!
