PXD035072

PXD035072 is an original dataset announced via ProteomeXchange.

Title	Human spinal cord injury plasma LC-MSMS
Description	The primary aim of this work was to investigage the proteomic differences across spinal cord injury (SCI) patients who experience significant functional recovery relative to those who do not, to both better understand the pathophysiology and to identify potentially useful biomarkers of recovery. Blood samples were taken, following informed consent, from ASIA impairment scale (AIS) grade C "Improvers" (AIS grade improvement) (n=10 & n=9) and "Non-Improvers" (No AIS change) (n=7 & n=6), and AIS grade A (n=11 & n= 9) and D (n=11 & n=10) at <2 weeks ("Acute") and approx. 3 months ("Sub-acute") post-injury for a total of 73 samples. The samples were treated with ProteoMiner™ beads. Data dependent label-free LC-MSMS was used to characterise the proteome of the samples.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:38:21.615.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD035072
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Mateus Harrington
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2022-07-04 14:51:06	ID requested
1	2022-07-14 03:36:28	announced
2	2023-11-14 08:57:44	announced	2023-11-14: Updated project metadata.
⏵ 3	2024-10-22 05:38:22	announced	2024-10-22: Updated project metadata.

10.6019/PXD035072;

10.1101/2022.07.12.499696;

submitter keyword: Spinal cord injury, Human, Plasma,LC-MSMS

Karina Wright
contact affiliation	Keele University
contact email	karina.wright1@nhs.net
lab head
Mateus Harrington
contact affiliation	Cardiff University
contact email	Bernardo-HarringtonG@cardiff.ac.uk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/07/PXD035072

PRIDE project URI

• PRIDE
  1. PXD035072
     1. Label: PRIDE project
     2. Name: Human spinal cord injury plasma LC-MSMS