PXD035034

PXD035034 is an original dataset announced via ProteomeXchange.

Title	Cardiac Hypertensive-Cmpd17b (therapeutic)
Description	Formyl peptide receptors (FPR) play a critical role in the regulation of resolution of inflammation, an important mediator of hypertension-induced cardiac damage. We have previously discovered an FPR small-molecule prototype Cmpd17b exhibit cardioprotective effects against acute and severe cardiac inflammatory insults, but its impact on chronic cardiac inflammatory insult, such as hypertension, has not been explored. To investigate the therapeutic potential of our FPR agonist on mean arterial pressure (MAP), cardiac remodelling and function in hypertensive mice.
HostingRepository	PRIDE
AnnounceDate	2023-02-23
AnnouncementXML	Submission_2023-02-22_22:37:15.134.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	davidgreening
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	acetylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2022-06-30 07:23:36	ID requested
⏵ 1	2023-02-22 22:37:15	announced

Dataset with its publication pending

submitter keyword: Heart, Therapeutic, Proteomics, Remodelling, Function

DavidGreening
contact affiliation	Baker Heart & Diabetes Institute
contact email	david.greening@baker.edu.au
lab head
davidgreening
contact affiliation	Baker Heart and Diabetes Inst.
contact email	david.greening@baker.edu.au
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/02/PXD035034

PRIDE project URI

• PRIDE
  1. PXD035034
     1. Label: PRIDE project
     2. Name: Cardiac Hypertensive-Cmpd17b (therapeutic)