PXD035026

PXD035026 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Proteomics Characterization of Longitudinal CSF from ALS Fast and Slow Progressors
Description	Each CSF sample was concentrated and added to a multiple affinity removal spin cartridge .The eluates were subjected to a buffer exchange and proteins were reduced using DTT and alkylated using iodoacetamide. Digestions were performed using trypsin. CSF from patients with amyotrophic lateral sclerosis (ALS) was characterized via LC-MS/MS. Biomarkers were identified to differentiate fast and slow progressors.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_06:26:15.781.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Krystine Mansfield
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2022-06-30 07:01:15	ID requested
1	2024-01-26 07:39:31	announced
⏵ 2	2024-10-22 06:26:16	announced	2024-10-22: Updated project metadata.

Publication List

Vu L, Garcia-Mansfield K, Pompeiano A, An J, David-Dirgo V, Sharma R, Venugopal V, Halait H, Marcucci G, Kuo YH, Uechi L, Rockne RC, Pirrotte P, Bowser R, Proteomics and mathematical modeling of longitudinal CSF differentiates fast versus slow ALS progression. Ann Clin Transl Neurol, 10(11):2025-2042(2023) [pubmed]
10.1002/acn3.51890;

Vu L, Garcia-Mansfield K, Pompeiano A, An J, David-Dirgo V, Sharma R, Venugopal V, Halait H, Marcucci G, Kuo YH, Uechi L, Rockne RC, Pirrotte P, Bowser R, Proteomics and mathematical modeling of longitudinal CSF differentiates fast versus slow ALS progression. Ann Clin Transl Neurol, 10(11):2025-2042(2023) [pubmed]

10.1002/acn3.51890;

Keyword List

submitter keyword: Amyotrophic Lateral Sclerosis, mass spectrometry, CSF

submitter keyword: Amyotrophic Lateral Sclerosis, mass spectrometry, CSF

Contact List

Patrick Pirrotte
contact affiliation	Translational Genomics Research Institute (TGen)
contact email	ppirrotte@tgen.org
lab head
Krystine Mansfield
contact affiliation	TGen
contact email	kgarcia@tgen.org
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/01/PXD035026
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/01/PXD035026

PRIDE project URI

Repository Record List

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