PXD035005 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | The anti-metastatic effect of pyruvate dehydrogenase kinase 4 inhibition in bladder cancer via p-AKT, p-ERK, p-Src and p-JNK pathway |
Description | To confirm the anti-metastatic effect in bladder cancer cell lines, the PDK4 gene was knocked down and phosphorylated protein changes were compared through LC-MS/MS analysis. |
HostingRepository | PRIDE |
AnnounceDate | 2023-11-14 |
AnnouncementXML | Submission_2023-11-14_08:29:26.070.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Eunji Sung |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | phosphorylated residue |
Instrument | LTQ Orbitrap Velos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-06-30 03:17:22 | ID requested | |
1 | 2023-03-10 16:12:56 | announced | |
⏵ 2 | 2023-11-14 08:29:26 | announced | 2023-11-14: Updated project metadata. |
Publication List
Lee EH, Chung JW, Sung E, Yoon BH, Jeon M, Park S, Chun SY, Lee JN, Kim BS, Kim HT, Kim TH, Choi SH, Yoo ES, Kwon TG, Kang HW, Kim WJ, Yun SJ, Lee S, Ha YS, Anti-Metastatic Effect of Pyruvate Dehydrogenase Kinase 4 Inhibition in Bladder Cancer via the ERK, SRC, and JNK Pathways. Int J Mol Sci, 23(21):(2022) [pubmed] |
Keyword List
ProteomeXchange project tag: Cancer (B/D-HPP), Biology/Disease-Driven Human Proteome Project (B/D-HPP), Human Proteome Project |
submitter keyword: Human, bladder cancer, phosphoproteomics, LC-MS/MS |
Contact List
SangKyu Lee |
contact affiliation | College of Pharmacy, Kyungpook National University, 80 Daehak-ro, Buk-gu, Daegu 41566 Korea |
contact email | pharm239@gmail.com |
lab head | |
Eunji Sung |
contact affiliation | Kyungpook National Univertisy |
contact email | ssungeunji3@gmail.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/03/PXD035005 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD035005
- Label: PRIDE project
- Name: The anti-metastatic effect of pyruvate dehydrogenase kinase 4 inhibition in bladder cancer via p-AKT, p-ERK, p-Src and p-JNK pathway