PXD035005

PXD035005 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	The anti-metastatic effect of pyruvate dehydrogenase kinase 4 inhibition in bladder cancer via p-AKT, p-ERK, p-Src and p-JNK pathway
Description	To confirm the anti-metastatic effect in bladder cancer cell lines, the PDK4 gene was knocked down and phosphorylated protein changes were compared through LC-MS/MS analysis.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_08:29:26.070.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Eunji Sung
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	phosphorylated residue
Instrument	LTQ Orbitrap Velos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2022-06-30 03:17:22	ID requested
1	2023-03-10 16:12:56	announced
⏵ 2	2023-11-14 08:29:26	announced	2023-11-14: Updated project metadata.

Publication List

Lee EH, Chung JW, Sung E, Yoon BH, Jeon M, Park S, Chun SY, Lee JN, Kim BS, Kim HT, Kim TH, Choi SH, Yoo ES, Kwon TG, Kang HW, Kim WJ, Yun SJ, Lee S, Ha YS, Anti-Metastatic Effect of Pyruvate Dehydrogenase Kinase 4 Inhibition in Bladder Cancer via the ERK, SRC, and JNK Pathways. Int J Mol Sci, 23(21):(2022) [pubmed]

Lee EH, Chung JW, Sung E, Yoon BH, Jeon M, Park S, Chun SY, Lee JN, Kim BS, Kim HT, Kim TH, Choi SH, Yoo ES, Kwon TG, Kang HW, Kim WJ, Yun SJ, Lee S, Ha YS, Anti-Metastatic Effect of Pyruvate Dehydrogenase Kinase 4 Inhibition in Bladder Cancer via the ERK, SRC, and JNK Pathways. Int J Mol Sci, 23(21):(2022) [pubmed]

Keyword List

ProteomeXchange project tag: Cancer (B/D-HPP), Biology/Disease-Driven Human Proteome Project (B/D-HPP), Human Proteome Project
submitter keyword: Human, bladder cancer, phosphoproteomics, LC-MS/MS

ProteomeXchange project tag: Cancer (B/D-HPP), Biology/Disease-Driven Human Proteome Project (B/D-HPP), Human Proteome Project

submitter keyword: Human, bladder cancer, phosphoproteomics, LC-MS/MS

Contact List

SangKyu Lee
contact affiliation	College of Pharmacy, Kyungpook National University, 80 Daehak-ro, Buk-gu, Daegu 41566 Korea
contact email	pharm239@gmail.com
lab head
Eunji Sung
contact affiliation	Kyungpook National Univertisy
contact email	ssungeunji3@gmail.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/03/PXD035005
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/03/PXD035005

PRIDE project URI

Repository Record List

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