PXD034946

PXD034946 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Rapid proximity biotinylation of the Plasmodium falciparum exported protein, SBP1
Description	The deadly human malaria-causing parasite, Plasmodium falciparum relies on its capacity to completely remodel its host red blood cell (RBC) through the export of several hundred parasite proteins across several membranes to the RBC.We fused the exported membrane protein, skeleton binding protein 1 (SBP1), with the rapid, efficient, promiscuous biotin ligase known as TurboID (SBP1TbID). Using time-resolved, proximity biotinylation and label-free quantitative proteomics, we identified early (pre-export) interactors and late (post-export) interactors of SBP1TbID.
HostingRepository	MassIVE
AnnounceDate	2023-10-06
AnnouncementXML	Submission_2023-10-06_04:44:45.696.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Vasant Muralidharan
SpeciesList	scientific name: Plasmodium falciparum NF54; NCBI TaxID: 5843;
ModificationList	Biotin
Instrument	Orbitrap Fusion

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2022-06-27 17:05:06	ID requested
⏵ 1	2023-10-06 04:44:46	announced

Publication List

Anaguano D, Dedkhad W, Brooks CF, Cobb DW, Muralidharan V, Time-resolved proximity biotinylation implicates a porin protein in export of transmembrane malaria parasite effectors. J Cell Sci, 136(20):(2023) [pubmed]

Anaguano D, Dedkhad W, Brooks CF, Cobb DW, Muralidharan V, Time-resolved proximity biotinylation implicates a porin protein in export of transmembrane malaria parasite effectors. J Cell Sci, 136(20):(2023) [pubmed]

Keyword List

submitter keyword: malaria, protein export, skeleton binding protein 1, plasmodium, protein trafficking, turboID

submitter keyword: malaria, protein export, skeleton binding protein 1, plasmodium, protein trafficking, turboID

Contact List

Vasant Muralidharan
contact affiliation	University of Georgia
contact email	vasant@uga.edu
lab head
Vasant Muralidharan
contact affiliation	University of Georgia
contact email	vasant@uga.edu
dataset submitter

Full Dataset Link List

MassIVE dataset URI
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MassIVE dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000089743/