PXD034940

PXD034940 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	A proteomic platform unveils PGK1 and 2 as potential target for Tatridin A
Description	A multi-disciplinary strategy has been developed and applied for identifying Tatridin A target(s) to fully address its mechanism of action, based on drug affinity response target stability and targeted limited proteolysis. Both approaches point to the identification of PGK 1 and 2 (phospoglicerate kinase 1 and 2) as major Tatridin A targets in THP-1 cell lysates, giving also detailed insights into the ligand/proteins interaction sites.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:59:13.749.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Giusy Ferraro
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2022-06-27 02:53:24	ID requested
1	2023-07-31 05:15:45	announced
⏵ 2	2024-10-22 05:59:14	announced	2024-10-22: Updated project metadata.

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: proteomics, natural compound, tatridin A,Phosphoglicerate kinase 1 and 2, target identification

submitter keyword: proteomics, natural compound, tatridin A,Phosphoglicerate kinase 1 and 2, target identification

Contact List

Maria Chiara Monti
contact affiliation	Department of Pharmacy, University of Salerno, 84084 Fisciano, Italy
contact email	mcmonti@unisa.it
lab head
Giusy Ferraro
contact affiliation	Università degli Studi di Salerno
contact email	gferraro@unisa.it
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/07/PXD034940
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/07/PXD034940

PRIDE project URI

Repository Record List

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