PXD034847

PXD034847 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	A comprehensive and quantitative interactome of RAS
Description	We investigated a comprehensive and quantitative interactome of RAS, a protein found to be a driver of many human cancers. This resource identifies interactors of the active form of RAS (nucleotide-dependent) as well as isoform-specific (KRAS, HRAS, and NRAS) interactors of RAS. Several of the proteins identified were confirmed as being important for cancer cell viability and senescence.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_06:55:26.674.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Sheng Zhang
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2022-06-22 15:06:23	ID requested
1	2022-10-13 02:46:31	announced
⏵ 2	2023-11-14 06:55:27	announced	2023-11-14: Updated project metadata.

Publication List

Miller SP, Maio G, Zhang X, Badillo Soto FS, Zhu J, Ramirez SZ, Lin H, A Proteomic Approach Identifies Isoform-Specific and Nucleotide-Dependent RAS Interactions. Mol Cell Proteomics, 21(8):100268(2022) [pubmed]

Miller SP, Maio G, Zhang X, Badillo Soto FS, Zhu J, Ramirez SZ, Lin H, A Proteomic Approach Identifies Isoform-Specific and Nucleotide-Dependent RAS Interactions. Mol Cell Proteomics, 21(8):100268(2022) [pubmed]

Keyword List

submitter keyword: RAS, Cell viability, Interactome, SILAC labeling, Sebescence

submitter keyword: RAS, Cell viability, Interactome, SILAC labeling, Sebescence

Contact List

Sheng Zhang
contact affiliation	Proteomics and Metabolomics Facility, Institute of Biotechnology, Cornell University USA
contact email	sz14@cornell.edu
lab head
Sheng Zhang
contact affiliation	Cornell University
contact email	sz14@cornell.edu
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/10/PXD034847
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/10/PXD034847

PRIDE project URI

Repository Record List

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