PXD034836

PXD034836 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Exploring direct and indirect targets of current antileishmanial drugs using a novel thermal proteomics profiling approach
Description	We have implemented a novel approach based on thermal proteome profiling (TPP) to further characterize the mode of action of antileishmanials antimony, miltefosine and amphotericin B, as well as to better understand the mechanisms of drug resistance deployed by Leishmania.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_08:57:18.010.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD034836
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Ana Ibarra Meneses
SpeciesList	scientific name: Leishmania infantum JPCM5; NCBI TaxID: 435258;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap Velos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2022-06-22 02:35:07	ID requested
1	2022-07-22 08:47:14	announced
⏵ 2	2023-11-14 08:57:18	announced	2023-11-14: Updated project metadata.

Publication List

10.6019/PXD034836;

10.6019/PXD034836;

Keyword List

submitter keyword: Leishmania
Leishmaniasis
Thermal proteome profiling
Drug resistance
Proteomics
Antimony
Miltefosine
Amphotericin B

submitter keyword: Leishmania

Leishmaniasis

Thermal proteome profiling

Drug resistance

Proteomics

Antimony

Miltefosine

Amphotericin B

Contact List

Christopher Fernandez-Prada (CFP-Lab)
contact affiliation	University of Montréal
contact email	christopher.fernandez.prada@umontreal.ca
lab head
Ana Ibarra Meneses
contact affiliation	University of Montreal
contact email	ana.victoria.ibarra.meneses@umontreal.ca
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/07/PXD034836
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/07/PXD034836

PRIDE project URI

Repository Record List

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