PXD034781

PXD034781 is an original dataset announced via ProteomeXchange.

Title	Mannose receptor (CD206) N-glycosylation
Description	To explore the influence of glycosylation on mannose receptor (MR) binding to glycan ligands, we used the mouse CTLD4-7, fused to the Fc-portion of human IgG (MR-Fc) and human full-length MR. A detailed N- and O-glycopeptide analysis was performed using tryptic glycopeptides. In addition the samples were partially treated with different exoglycosidases to increase glycopeptide coverage.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_08:36:37.880.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Kathrin Stavenhagen
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2022-06-21 05:01:17	ID requested
1	2023-03-10 20:12:10	announced
⏵ 2	2023-11-14 08:36:38	announced	2023-11-14: Updated project metadata.

Stavenhagen K, Mehta AY, Laan L, Gao C, Heimburg-Molinaro J, van Die I, Cummings RD, N-glycosylation of mannose receptor (CD206) regulates glycan binding by C-type lectin domains. J Biol Chem, 298(12):102591(2022) [pubmed]

submitter keyword: glycosylation, O-linked glycosylation, mass spectrometry, glycoproteomics, glycan microarray,Mannose receptor, glycobiology, N-linked glycosylation, lectin

Richard D. Cummungs
contact affiliation	Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
contact email	rcummin1@bidmc.harvard.edu
lab head
Kathrin Stavenhagen
contact affiliation	Beth Israel Deaconess Medical Center, Harvard Medical School
contact email	kathrin.stavenhagen@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/03/PXD034781

PRIDE project URI

• PRIDE
  1. PXD034781
     1. Label: PRIDE project
     2. Name: Mannose receptor (CD206) N-glycosylation