PXD034631

PXD034631 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Changes to SUMO-modified proteome and total cellular proteome during EBV ractivation in AGS gastric carcinoma cells
Description	To monitor changes to cellular and viral SUMO-modified proteins during EBV reactivation. SUMO1 and SUMO2 conjugates were studied using KGG mutant forms of SUMO and GG-K specific antibody enrichment of SUMO modified peptides. Time-points of 12h and 24h post-reactivation were monitored. Total cellular proteome was also analysed to study changes to the total protein levels of proteins under the same conditions.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:48:38.016.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Mike Tatham
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	phosphorylated residue; sumoylated lysine; iodoacetamide derivatized residue
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2022-06-17 08:08:24	ID requested
1	2023-06-19 03:27:31	announced
2	2024-08-02 02:16:24	announced	2024-08-02: Updated project metadata.
⏵ 3	2024-10-22 05:48:38	announced	2024-10-22: Updated project metadata.

Publication List

10.1371/journal.ppat.1011477;
De La Cruz-Herrera CF, Tatham MH, Siddiqi UZ, Shire K, Marcon E, Greenblatt JF, Hay RT, Frappier L, Changes in SUMO-modified proteins in Epstein-Barr virus infection identifies reciprocal regulation of TRIM24/28/33 complexes and the lytic switch BZLF1. PLoS Pathog, 19(7):e1011477(2023) [pubmed]

10.1371/journal.ppat.1011477;

De La Cruz-Herrera CF, Tatham MH, Siddiqi UZ, Shire K, Marcon E, Greenblatt JF, Hay RT, Frappier L, Changes in SUMO-modified proteins in Epstein-Barr virus infection identifies reciprocal regulation of TRIM24/28/33 complexes and the lytic switch BZLF1. PLoS Pathog, 19(7):e1011477(2023) [pubmed]

Keyword List

submitter keyword: SUMO Epstein-Barr Virus EBVHuman Herpes Virus 4 HHV4

submitter keyword: SUMO Epstein-Barr Virus EBVHuman Herpes Virus 4 HHV4

Contact List

Ronald T. Hay
contact affiliation	Professor of Molecular Biology, University of Dundee
contact email	r.t.hay@dundee.ac.uk
lab head
Mike Tatham
contact affiliation	University of Dundee
contact email	m.tatham@dundee.ac.uk
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/06/PXD034631
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/06/PXD034631

PRIDE project URI

Repository Record List

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