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PXD034539

PXD034539 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleDIA acquisition of the immunopeptidomes of C1R-B*57:01 and C1R-A*02:01 cell lines
DescriptionImmunopeptidomes are the peptide repertoires bound by the molecules encoded by the major histocompatibility complex (MHC) (human leukocyte antigen (HLA) in humans). These HLA-peptide complexes are presented on the cell surface for immune T cell recognition. Immunopeptidomics utilizes tandem mass spectrometry (MS/MS) to identify and quantify peptides bound to HLA molecules. Data-independent acquisition (DIA) has emerged as a powerful strategy for deep proteome-wide profiling, but DIA application to immunopeptidomics analyses has so far seen limited use. The dataset deposited here contains the DIA data of the HLA-bound peptides purified and isolated from C1R-B*57:01 and C1R-A*02:01 cell lines.
HostingRepositoryPRIDE
AnnounceDate2023-02-13
AnnouncementXMLSubmission_2023-02-13_03:19:35.021.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterMohammadShahbazy
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListmonohydroxylated residue; deamidated residue
InstrumentQ Exactive; Orbitrap Fusion
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-06-15 05:15:02ID requested
12023-02-13 03:19:35announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Mass spectrometry
Immunopeptidomics
DIA
Software tools benchmark
HLA-bound peptides
Spectral library
Contact List
Anthony W.Purcell
contact affiliationDepartment of Biochemistry and Molecular Biology & Infection and Immunity Program, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia
contact emailanthony.purcell@monash.edu
lab head
MohammadShahbazy
contact affiliationBiomedicine Discovery Institute and Department of Biochemistry & Molecular Biology, Monash University, Clayton, VIC 3800, Australia
contact emailmohammad.shahbazy@monash.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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