PXD034539 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | DIA acquisition of the immunopeptidomes of C1R-B*57:01 and C1R-A*02:01 cell lines |
Description | Immunopeptidomes are the peptide repertoires bound by the molecules encoded by the major histocompatibility complex (MHC) (human leukocyte antigen (HLA) in humans). These HLA-peptide complexes are presented on the cell surface for immune T cell recognition. Immunopeptidomics utilizes tandem mass spectrometry (MS/MS) to identify and quantify peptides bound to HLA molecules. Data-independent acquisition (DIA) has emerged as a powerful strategy for deep proteome-wide profiling, but DIA application to immunopeptidomics analyses has so far seen limited use. The dataset deposited here contains the DIA data of the HLA-bound peptides purified and isolated from C1R-B*57:01 and C1R-A*02:01 cell lines. |
HostingRepository | PRIDE |
AnnounceDate | 2023-02-13 |
AnnouncementXML | Submission_2023-02-13_03:19:35.021.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | MohammadShahbazy |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | monohydroxylated residue; deamidated residue |
Instrument | Q Exactive; Orbitrap Fusion |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-06-15 05:15:02 | ID requested | |
⏵ 1 | 2023-02-13 03:19:35 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Mass spectrometry |
Immunopeptidomics |
DIA |
Software tools benchmark |
HLA-bound peptides |
Spectral library |
Contact List
Anthony W.Purcell |
contact affiliation | Department of Biochemistry and Molecular Biology & Infection and Immunity Program, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia |
contact email | anthony.purcell@monash.edu |
lab head | |
MohammadShahbazy |
contact affiliation | Biomedicine Discovery Institute and Department of Biochemistry & Molecular Biology, Monash University, Clayton, VIC 3800, Australia |
contact email | mohammad.shahbazy@monash.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/02/PXD034539 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD034539
- Label: PRIDE project
- Name: DIA acquisition of the immunopeptidomes of C1R-B*57:01 and C1R-A*02:01 cell lines