PXD034527

PXD034527 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Mass spectrometry analysis of in vitro Tau ubiquitination by the UBA1/Hsp70/CHIP machinery
Description	We aimed at characterizing which lysines on Tau were ubiquitinated by the UBA1/Hsp70/CHIP machinery. We also determined the ubiquitin linkages of the assembled Tau chains.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_06:46:09.941.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Dorothea Anrather
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	ubiquitination signature dipeptidyl lysine
Instrument	Orbitrap Exploris 480

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2022-06-15 03:17:26	ID requested
1	2024-06-18 00:44:30	announced
⏵ 2	2024-10-22 06:46:10	announced	2024-10-22: Updated project metadata.

Publication List

Ferrari L, Bauer B, Qiu Y, Schuschnig M, Klotz S, Anrather D, Juretschke T, Beli P, Gelpi E, Martens S, Tau fibrils evade autophagy by excessive p62 coating and TAX1BP1 exclusion. Sci Adv, 10(24):eadm8449(2024) [pubmed]
10.1126/sciadv.adm8449;

Ferrari L, Bauer B, Qiu Y, Schuschnig M, Klotz S, Anrather D, Juretschke T, Beli P, Gelpi E, Martens S, Tau fibrils evade autophagy by excessive p62 coating and TAX1BP1 exclusion. Sci Adv, 10(24):eadm8449(2024) [pubmed]

10.1126/sciadv.adm8449;

Keyword List

submitter keyword: Ubiquitination, Protein Degradation, Alzheimer’s Disease,Tau

submitter keyword: Ubiquitination, Protein Degradation, Alzheimer’s Disease,Tau

Contact List

Sascha Martens
contact affiliation	Max Perutz Labs, University of Vienna, Vienna BioCenter, Vienna, Austria
contact email	sascha.martens@univie.ac.at
lab head
Dorothea Anrather
contact affiliation	Max Perutz Labs, Mass Spectrometry Facility, University of Vienna
contact email	dorothea.anrather@univie.ac.at
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/06/PXD034527
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/06/PXD034527

PRIDE project URI

Repository Record List

[ + ]