PXD034527 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Mass spectrometry analysis of in vitro Tau ubiquitination by the UBA1/Hsp70/CHIP machinery |
Description | We aimed at characterizing which lysines on Tau were ubiquitinated by the UBA1/Hsp70/CHIP machinery. We also determined the ubiquitin linkages of the assembled Tau chains. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_06:46:09.941.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Dorothea Anrather |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | ubiquitination signature dipeptidyl lysine |
Instrument | Orbitrap Exploris 480 |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-06-15 03:17:26 | ID requested | |
1 | 2024-06-18 00:44:30 | announced | |
⏵ 2 | 2024-10-22 06:46:10 | announced | 2024-10-22: Updated project metadata. |
Publication List
Ferrari L, Bauer B, Qiu Y, Schuschnig M, Klotz S, Anrather D, Juretschke T, Beli P, Gelpi E, Martens S, Tau fibrils evade autophagy by excessive p62 coating and TAX1BP1 exclusion. Sci Adv, 10(24):eadm8449(2024) [pubmed] |
10.1126/sciadv.adm8449; |
Keyword List
submitter keyword: Ubiquitination, Protein Degradation, Alzheimer’s Disease,Tau |
Contact List
Sascha Martens |
contact affiliation | Max Perutz Labs, University of Vienna, Vienna BioCenter, Vienna, Austria |
contact email | sascha.martens@univie.ac.at |
lab head | |
Dorothea Anrather |
contact affiliation | Max Perutz Labs, Mass Spectrometry Facility, University of Vienna |
contact email | dorothea.anrather@univie.ac.at |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/06/PXD034527 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD034527
- Label: PRIDE project
- Name: Mass spectrometry analysis of in vitro Tau ubiquitination by the UBA1/Hsp70/CHIP machinery