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PXD034527

PXD034527 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleMass spectrometry analysis of in vitro Tau ubiquitination by the UBA1/Hsp70/CHIP machinery
DescriptionWe aimed at characterizing which lysines on Tau were ubiquitinated by the UBA1/Hsp70/CHIP machinery. We also determined the ubiquitin linkages of the assembled Tau chains.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_06:46:09.941.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterDorothea Anrather
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListubiquitination signature dipeptidyl lysine
InstrumentOrbitrap Exploris 480
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-06-15 03:17:26ID requested
12024-06-18 00:44:30announced
22024-10-22 06:46:10announced2024-10-22: Updated project metadata.
Publication List
Ferrari L, Bauer B, Qiu Y, Schuschnig M, Klotz S, Anrather D, Juretschke T, Beli P, Gelpi E, Martens S, Tau fibrils evade autophagy by excessive p62 coating and TAX1BP1 exclusion. Sci Adv, 10(24):eadm8449(2024) [pubmed]
10.1126/sciadv.adm8449;
Keyword List
submitter keyword: Ubiquitination, Protein Degradation, Alzheimer’s Disease,Tau
Contact List
Sascha Martens
contact affiliationMax Perutz Labs, University of Vienna, Vienna BioCenter, Vienna, Austria
contact emailsascha.martens@univie.ac.at
lab head
Dorothea Anrather
contact affiliationMax Perutz Labs, Mass Spectrometry Facility, University of Vienna
contact emaildorothea.anrather@univie.ac.at
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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