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PXD034508

PXD034508 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleIdentification of cell membrane proteins involved in dsRNA internalization
DescriptionCellular uptake of dsRNA from the environment is a widespread phenomenon among insects. In Drosophila and in honeybees, the injection and the ingestion respectively of dsRNA against a viral sequence is sufficient to hinder virus replication. We wanted to identify cell surface proteins that bind to extracellular dsRNA, mediating its internalization. To this end, we developed an unconventional co-immunoprecipitation protocol followed by proteomics analysis.
HostingRepositoryPRIDE
AnnounceDate2025-04-11
AnnouncementXMLSubmission_2025-04-11_05:35:48.541.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD034508
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterYann Verdier
SpeciesList scientific name: Drosophila melanogaster (Fruit fly); NCBI TaxID: 7227;
ModificationListiodoacetamide derivatized residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-06-14 09:23:44ID requested
12025-04-11 05:35:48announced
Publication List
10.6019/PXD034508;
Keyword List
submitter keyword: RNA binding,drosophila
Contact List
Joelle Vinh
contact affiliationUMR8249 CNRS ESPCI
contact emailjoelle.vinh@espci.fr
lab head
Yann Verdier
contact affiliationSMBP
contact emailyann.verdier@espci.fr
dataset submitter
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Dataset FTP location
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PRIDE project URI
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