PXD034269

PXD034269 is an original dataset announced via ProteomeXchange.

Title	Mouse Cardiac Proteomics and β-hydroxybutyrylation omics Studies
Description	β-Hydroxybutyrylation (kbhb) is a new type of post-translational modification(PTM) of lysine acylation. In recent years, kbhb modification has been shown to be involved in energy metabolism, tumor metabolism, DNA damage repair and other processes. Currently, lysine β-hydroxybutyrylation has not been studied in cardiac tissue. In this study, we performed proteomic and β-hydroxybutyrylation modification omics analysis of mouse heart tissue based on LC-MS/MS analysis. These data provide the first mammalian cardiac kbhb dataset and provide new directions for further investigation of the function of kbhb in non-histone proteins.
HostingRepository	iProX
AnnounceDate	2023-03-14
AnnouncementXML	Submission_2024-03-20_00:14:20.933.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yanqiu Xing
SpeciesList	scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2022-06-02 01:57:53	ID requested
⏵ 1	2024-03-20 00:14:21	announced

Ding WJ, Li XH, Tang CM, Yang XC, Sun Y, Song YP, Ling MY, Yan R, Gao HQ, Zhang WH, Yu N, Feng JC, Zhang Z, Xing YQ, 2 Knockout Mice. Mol Cell Proteomics, 22(2):100494(2023) [pubmed]

submitter keyword: heart, proteomics, β-hydroxybutyrylation modification omics

Yanqiu Xing
contact affiliation	Qilu Hospital of Shandong University
contact email	xingyanqiu@sina.com
lab head
Yanqiu Xing
contact affiliation	Qilu Hospital of Shandong University
contact email	xingyanqiu@sina.com
dataset submitter

iProX dataset URI