PXD034188

PXD034188 is an original dataset announced via ProteomeXchange.

Title	Proteome analysis of transgenic 1D1a mice
Description	T cells specifically recognize an antigen with a T cell receptor (TCR) consisting of α- and β-chain. The transgenic 1D1a mice were generated on the genetic background of the B10.D2(R101) line and expressed in their T cells the α-chain TCR (TCRα) specific to the allogeneic MHC molecule Н2-Kb. To evaluate effects of TCRα transgenesis on the qualitative and quantitative composition of plasma proteins, comparative proteome analysis was performed for both female and male transgenic 1D1a and wild-type B10.D2(R101) mice aged 3-, 6-, and 12-months.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_08:46:03.925.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Rustam Ziganshin
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	acetylated residue; monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2022-05-29 14:07:35	ID requested
1	2023-05-10 09:39:26	announced
⏵ 2	2023-11-14 08:46:09	announced	2023-11-14: Updated project metadata.

Kalinina AA, Ziganshin RK, Silaeva YY, Sharova NI, Nikonova MF, Persiyantseva NA, Gorkova TG, Antoshina EE, Trukhanova LS, Donetskova AD, Komogorova VV, Litvina MM, Mitin AN, Zamkova MA, Bruter AV, Khromykh LM, Kazansky DB, Expression in Transgenic Mice. Int J Mol Sci, 24(7):(2023) [pubmed]

submitter keyword: LC-MSMS, blood plasma,transgenic 1D1a mice

Dmitry Kazansky
contact affiliation	Laboratory of Regulatory Mechanisms in Immunity Institute of Carcinogenesis Federal State Budgetary Institution "N. N. Blokhin National Medical Research Center of Oncology" of the Ministry of Health of the Russian Federation
contact email	kazansky1@yandex.ru
lab head
Rustam Ziganshin
contact affiliation	Shemyakin-Ovchinnikov Institute of bioorganic chemistry Russian Academy of Sciences
contact email	rustam.ziganshin@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/05/PXD034188

PRIDE project URI

• PRIDE
  1. PXD034188
     1. Label: PRIDE project
     2. Name: Proteome analysis of transgenic 1D1a mice