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PXD034161

PXD034161 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleRNA pulldown-MS, Dlg4 RNA in mHippoE-2 cells
DescriptionGoal was to identify RNA-binding proteins with a preference for m6A-modified RNA using an RNA bait generated from a known m6A site in the Dlg4 (PSD-95) mRNA 3`-UTR. By comparison of differential enrichment between m6A-RNA pulldown fractions and A-RNA or no RNA fractions, we can identify m6A-binding proteins.
HostingRepositoryPRIDE
AnnounceDate2023-11-14
AnnouncementXMLSubmission_2023-11-14_07:02:27.185.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD034161
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterKate Meyer
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListiodoacetamide derivatized residue
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-05-27 06:35:27ID requested
12022-10-13 02:45:12announced
22023-11-14 07:02:28announced2023-11-14: Updated project metadata.
Publication List
10.6019/PXD034161;
Choi SH, Flamand MN, Liu B, Zhu H, Hu M, Wang M, Sewell J, Holley CL, Al-Hashimi HM, Meyer KD, A-binding protein that affects neuronal differentiation and the splicing of a subset of mRNAs. Cell Rep, 40(9):111293(2022) [pubmed]
Keyword List
submitter keyword: pulldown,m6A, RNA, LC-MS/MS
Contact List
Kate Meyer
contact affiliationAssistant Professor of Biochemistry Assistant Professor in Neurobiology Nanaline Duke Room 155 Box 3711, DUMC Durham, NC 27710
contact emailkate.meyer@duke.edu
lab head
Kate Meyer
contact affiliationMeyer Laboratory, Department of Biochemistry Duke University, School of Medicine
contact emailkate.meyer@duke.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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