PXD034159 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | RNA pulldown-MS, Dlg4 RNA in mouse brain |
Description | Goal was to identify RNA-binding proteins with a preference for m6A-modified RNA using an RNA bait generated from a known m6A site in the Dlg4 (PSD-95) mRNA 3`-UTR. By comparison of differential enrichment between m6A-RNA pulldown fractions and A-RNA or no RNA fractions, we can identify m6A-binding proteins. |
HostingRepository | PRIDE |
AnnounceDate | 2023-11-14 |
AnnouncementXML | Submission_2023-11-14_07:05:58.745.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD034159 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Kate Meyer |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | iodoacetamide derivatized residue |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-05-27 06:32:37 | ID requested | |
1 | 2022-10-13 02:45:13 | announced | |
⏵ 2 | 2023-11-14 07:05:59 | announced | 2023-11-14: Updated project metadata. |
Publication List
Choi SH, Flamand MN, Liu B, Zhu H, Hu M, Wang M, Sewell J, Holley CL, Al-Hashimi HM, Meyer KD, A-binding protein that affects neuronal differentiation and the splicing of a subset of mRNAs. Cell Rep, 40(9):111293(2022) [pubmed] |
10.6019/PXD034159; |
Keyword List
submitter keyword: pulldown,m6A, RNA, LC-MS/MS |
Contact List
Kate Meyer |
contact affiliation | Assistant Professor of Biochemistry Assistant Professor of Neurobiology Nanaline Duke Room 155 Box 3711, DUMC Durham, NC 27710 |
contact email | kate.meyer@duke.edu |
lab head | |
Kate Meyer |
contact affiliation | Meyer Laboratory, Department of Biochemistry Duke University, School of Medicine |
contact email | kate.meyer@duke.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/10/PXD034159 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD034159
- Label: PRIDE project
- Name: RNA pulldown-MS, Dlg4 RNA in mouse brain