PXD034127

PXD034127 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	The eWAT ubiquitinome of wild type mice and Mdm2 adipocyte-specific knock-in mice fed high-fat diet
Description	The epididymal adipose tissue (eWAT) samples from wild type mice fed high-fat diet for 12 weeks (H_WT_E) and Mdm2 adipocyte-specific knock-in mice fed high-fat diet for 12 weeks (H_KI_E) were mixed separately, and subjected to ubiquitinome study by Label-free quantification and ubiquitination modification enrichment techniques, etc. The proteomics of mixed eWAT samples were performed in Jingjie PTM BioLab (Hangzhou) Co. Ltd (www.ptm-biolab.com.cn). The difference was determined by 1.5-fold-change criterion, FDR < 0.01.
HostingRepository	iProX
AnnounceDate	2022-05-26
AnnouncementXML	Submission_2022-09-27_20:54:55.436.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Xiaojun Liu
SpeciesList	scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationList	ubiquitination signature dipeptidyl lysine
Instrument	Q Exactive Plus

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2022-05-25 21:16:58	ID requested
1	2022-05-25 21:17:22	announced
⏵ 2	2022-09-27 20:54:56	announced	2022-09-28: Update publication information.

Publication List

Zhao W, Xu Q, Yang J, Xie X, Li C, Zhang W, Chen E, Guo Y, Gao M, Shi J, Zhang H, Yao H, Li M, Yan L, Fang F, Wu W, Liu X, Murine double minute 2 aggravates adipose tissue dysfunction through ubiquitin-mediated six-transmembrane epithelial antigen of prostate 4 degradation. iScience, 25(7):104544(2022) [pubmed]

Zhao W, Xu Q, Yang J, Xie X, Li C, Zhang W, Chen E, Guo Y, Gao M, Shi J, Zhang H, Yao H, Li M, Yan L, Fang F, Wu W, Liu X, Murine double minute 2 aggravates adipose tissue dysfunction through ubiquitin-mediated six-transmembrane epithelial antigen of prostate 4 degradation. iScience, 25(7):104544(2022) [pubmed]

Keyword List

submitter keyword: Ubiquitinome, eWAT, Mdm2, Mice, High-fat diet

submitter keyword: Ubiquitinome, eWAT, Mdm2, Mice, High-fat diet

Contact List

Prof. Xiaojun Liu
contact affiliation	Institute of Basic Medical Sciences Chinese Academy of Medical Sciences & School of Basic Medicine Peking Union Medical College
contact email	xiaojunliu@ibms.pumc.edu.cn
lab head
Xiaojun Liu
contact affiliation	Institute of Basic Medical Sciences Chinese Academy of Medical Sciences & School of Basic Medicine Peking Union Medical College
contact email	xiaojunliu@ibms.pumc.edu.cn
dataset submitter

Full Dataset Link List

iProX dataset URI

iProX dataset URI